PDB entry 1zrq

View 1zrq on RCSB PDB site
Description: Escherichia coli Methylenetetrahydrofolate Reductase (reduced) complexed with NADH, pH 6.0
Class: oxidoreductase
Keywords: tim barrel, flavin, reductase, nadh, oxidoreductase
Deposited on 2005-05-19, released 2005-08-09
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: N/A
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zrqa_
  • Chain 'B':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zrqb_
  • Chain 'C':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1zrqc_
  • Heterogens: SO4, FAD, NAI, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zrqA (A:)
msffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zrqA (A:)
ffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtyga
drthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgdlpemyas
dlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylr
frdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvg
aniamdmvkilsregvkdfhfytlnraemsyaichtlgvrp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zrqB (B:)
msffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zrqB (B:)
ffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtyga
nsgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgdlp
pemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffd
vesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddae
trklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1zrqC (C:)
msffhasqrdalnqslaevqgqinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zrqC (C:)
qinvsfeffpprtsemeqtlwnsidrlsslkpkfvsvtygansgerdrthsiikgikdrt
gleaaphltcidatpdelrtiardywnngirhivalrgdlppemyasdlvtllkevadfd
isvaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylrfrdrcvsagidve
iipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvganiamdmvkilsr
egvkdfhfytlnraemsyaichtlgvrp