PDB entry 1zro

View 1zro on RCSB PDB site
Description: Crystal structure of EBA-175 Region II (RII) crystallized in the presence of (alpha)2,3-sialyllactose
Class: cell invasion
Keywords: EBA-175, RII, DBL, erythrocyte, invasion, host, malaria, disease, glycophorin, glycan, sialic acid, binding, sialyllactose
Deposited on 2005-05-19, released 2005-08-09
The last revision prior to the SCOP 1.73 freeze date was dated 2005-08-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.25 Å
R-factor: 0.217
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: erythrocyte binding antigen region II
    Species: Plasmodium falciparum
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q25735
      • engineered (49)
      • engineered (194)
      • engineered (205)
    Domains in SCOP 1.73: d1zroa1, d1zroa2
  • Chain 'B':
    Compound: erythrocyte binding antigen region II
    Species: Plasmodium falciparum
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q25735
      • engineered (49)
      • engineered (194)
      • engineered (205)
    Domains in SCOP 1.73: d1zrob1, d1zrob2
  • Heterogens: SO4, CL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zroA (A:)
grqtssnnevlsncrekrkgmkwdckkkndrsnyvcipdrriqlcivnlaiiktytketm
kdhfieaskkesqlllkkndnkynskfcndlknsfldyghlamgndmdfggystkaenki
qevfkgahgeisehkiknfrkkwwnefreklweamlsehknninncknipqeelqitqwi
kewhgefllerdnraklpkskcknnalyeacekecidpcmkyrdwiirskfewhtlskey
etqkvpkenaenylikisenkndakvslllnncdaeyskycdckhtttlvksvlngndnt
ikekrehidlddfskfgcdknsvdtntkvweckkpyklstkdvcvpprrqelclgnidri
ydknllmikehilaiaiyesrilkrkyknkddkevckiinktfadirdiiggtdywndls
nrklvgkintnsnyvhrnkqndklfrdewwkvikkdvwnviswvfkdktvckeddienip
qffrwfsewgddycqdktkmietlkveckekpceddnckrkcnsykewiskkkeeynkqa
kqyqeyqkgnnykmysefksikpevylkkysekcsnlnfedefkeelhsdyknkctmcpe
vk

    Sequence, based on observed residues (ATOM records): (download) 
    >1zroA (A:)
nevlsncrekrkgmkwdckkkndrsnyvcipdrriqlcivnlaiiktytketmkdhfiea
skkesqlllkkndnkynskfcndlknsfldyghlamgndmdfggystkaenkiqevfkga
hgeisehkiknfrkkwwnefreklweamlsehknnicknipqeelqitqwikewhgefll
erdnraklpkskcknnalyeacekecidpcmkyrdwiirskfewhtlskeyetqkvpken
aenylikisenkndakvslllnncdaeyskycdckhtttlvksvlngndntikekrehid
lddfskfgcdknsvdtntkvweckkpyklstkdvcvpprrqelclgnidriydknllmik
ehilaiaiyesrilkrkyknkddkevckiinktfadirdiiggtdywndlsnrklvgkin
tnsnyvhrnkqndklfrdewwkvikkdvwnviswvfkdktvckeddienipqffrwfsew
gddycqdktkmietlkvecceddnckrkcnsykewiskkkeeynkqakqyqeyqkgnnyk
mysefksikpevylkkysekcsnlnfedefkeelhsdyknkctmcpev

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zroB (B:)
grqtssnnevlsncrekrkgmkwdckkkndrsnyvcipdrriqlcivnlaiiktytketm
kdhfieaskkesqlllkkndnkynskfcndlknsfldyghlamgndmdfggystkaenki
qevfkgahgeisehkiknfrkkwwnefreklweamlsehknninncknipqeelqitqwi
kewhgefllerdnraklpkskcknnalyeacekecidpcmkyrdwiirskfewhtlskey
etqkvpkenaenylikisenkndakvslllnncdaeyskycdckhtttlvksvlngndnt
ikekrehidlddfskfgcdknsvdtntkvweckkpyklstkdvcvpprrqelclgnidri
ydknllmikehilaiaiyesrilkrkyknkddkevckiinktfadirdiiggtdywndls
nrklvgkintnsnyvhrnkqndklfrdewwkvikkdvwnviswvfkdktvckeddienip
qffrwfsewgddycqdktkmietlkveckekpceddnckrkcnsykewiskkkeeynkqa
kqyqeyqkgnnykmysefksikpevylkkysekcsnlnfedefkeelhsdyknkctmcpe
vk

    Sequence, based on observed residues (ATOM records): (download) 
    >1zroB (B:)
nevlsncrekrkgmkwdckkkndrsnyvcipdrriqlcivnlaiiktytketmkdhfiea
skkesqlllkkndnkynskfcndlknsfldyghlamgndmdfggystkaenkiqevfkga
hgeisehkiknfrkkwwnefreklweamlsehknnicknipqeelqitqwikewhgefll
erdnraklpkskcknnalyeacekecidpcmkyrdwiirskfewhtlskeyetqkvpken
aenylikisenkndakvslllnncdaeyskycdckhtttlvksvlngndntikekrehid
lddfskfgcdknsvdtntkvweckkpyklstkdvcvpprrqelclgnidriydknllmik
ehilaiaiyesrilkrkyknkddkevckiinktfadirdiiggtdywndlsnrklvgkin
tnsnyvhrnkqndklfrdewwkvikkdvwnviswvfkdktvckeddienipqffrwfsew
gddycqdktkmietlkvecceddnckrkcnsykewiskkkeeynkqakqyqeyqkgnnyk
mysefksikpevylkkysekcsnlnfedefkeelhsdyknkctmcpev