PDB entry 1zq5

View 1zq5 on RCSB PDB site
Description: Crystal structure of human androgenic 17beta-hydroxysteroid dehydrogenase type 5 in complexed with a potent inhibitor EM1404
Class: oxidoreductase
Keywords: (alpha/beta)8 barrel, OXIDOREDUCTASE
Deposited on 2005-05-18, released 2006-12-12
The last revision prior to the SCOPe 2.03 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.3 Å
R-factor: 0.182
AEROSPACI score: 0.74 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Aldo-keto reductase family 1 member C3
    Species: Homo sapiens [TaxId:9606]
    Gene: AKR1C3, DDH1, KIAA0119, PGFS
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.03: d1zq5a_
  • Heterogens: ACT, E04, NAP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zq5A (A:)
mdskqqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeq
vglairskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspm
slkpgeelsptdengkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkp
glkykpvcnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpv
lcalakkhkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgld
rnlhyfnsdsfashpnypysdey

    Sequence, based on observed residues (ATOM records): (download) 
    >1zq5A (A:)
qqcvklndghfmpvlgfgtyappevprskalevtklaieagfrhidsahlynneeqvgla
irskiadgsvkredifytsklwstfhrpelvrpalenslkkaqldyvdlylihspmslkp
geelspngkvifdivdlcttweamekckdaglaksigvsnfnrrqlemilnkpglkykpv
cnqvechpyfnrsklldfckskdivlvaysalgsqrdkrwvdpnspvlledpvlcalakk
hkrtpalialryqlqrgvvvlaksyneqrirqnvqvfefqltaedmkaidgldrnlhyfn
sdsfashpnypysd