PDB entry 1zp4

View 1zp4 on RCSB PDB site
Description: Glu28Gln mutant of E. coli Methylenetetrahydrofolate Reductase (oxidized) complex with Methyltetrahydrofolate
Class: oxidoreductase
Keywords: tim barrel, methyltetrahydrofolate, flavin, reductase, oxidoreductase
Deposited on 2005-05-16, released 2005-08-09
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-11-16, with a file datestamp of 2011-11-11.
Experiment type: XRAY
Resolution: 1.85 Å
R-factor: 0.213
AEROSPACI score: 0.48 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00394
      • engineered (27)
    Domains in SCOPe 2.06: d1zp4a_
  • Chain 'B':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00394
      • engineered (27)
    Domains in SCOPe 2.06: d1zp4b_
  • Chain 'C':
    Compound: 5,10-Methylenetetrahydrofolate reductase
    Species: Escherichia coli [TaxId:562]
    Gene: METF
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00394
      • engineered (27)
    Domains in SCOPe 2.06: d1zp4c_
  • Heterogens: SO4, C2F, FAD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1zp4A (A:)
msffhasqrdalnqslaevqgqinvsfqffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zp4A (A:)
ffhasqrdalnqslaevqgqinvsfqffpprtsemeqtlwnsidrlsslkpkfvsvtygr
thsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgdlppgpemya
sdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesyl
rfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklv
ganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrp

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1zp4B (B:)
msffhasqrdalnqslaevqgqinvsfqffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zp4B (B:)
ffhasqrdalnqslaevqgqinvsfqffpprtsemeqtlwnsidrlsslkpkfvsvtyga
nsgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgdle
myasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganraitqfffdve
sylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetr
klvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrp

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1zp4C (C:)
msffhasqrdalnqslaevqgqinvsfqffpprtsemeqtlwnsidrlsslkpkfvsvty
gansgerdrthsiikgikdrtgleaaphltcidatpdelrtiardywnngirhivalrgd
lppgsgkpemyasdlvtllkevadfdisvaaypevhpeaksaqadllnlkrkvdaganra
itqfffdvesylrfrdrcvsagidveiipgilpvsnfkqakkfadmtnvripawmaqmfd
gldddaetrklvganiamdmvkilsregvkdfhfytlnraemsyaichtlgvrpgllehh
hhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1zp4C (C:)
qinvsfqffpprtsemeqtlwnsidrlsslkpkfvsvtygansgerdrthsiikgikdrt
gleaaphltcidatpdelrtiardywnngirhivalrgdlpemyasdlvtllkevadfdi
svaaypevhpeaksaqadllnlkrkvdaganraitqfffdvesylrfrdrcvsagidvei
ipgilpvsnfkqakkfadmtnvripawmaqmfdgldddaetrklvganiamdmvkilsre
gvkdfhfytlnraemsyaichtlgvrp