PDB entry 1zcm

View 1zcm on RCSB PDB site
Description: Human calpain protease core inhibited by ZLLYCH2F
Class: hydrolase
Keywords: Calcium binding, Hydrolase, Protease, Thiol protease
Deposited on 2005-04-12, released 2006-01-31
The last revision prior to the SCOP 1.73 freeze date was dated 2006-02-14, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.182
AEROSPACI score: 0.43 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Calpain 1, large [catalytic] subunit
    Species: HOMO SAPIENS
    Gene: CAPN1, CANPL1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P07384 (0-320)
      • engineered (180)
    Domains in SCOP 1.73: d1zcma1
  • Heterogens: CA, C1N, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1zcmA (A:)
naikylgqdyeqlrvrclqsgtlfrdeafppvpqslgykdlgpnssktygikwkrptell
snpqfivdgatrtdicqgalgdcwllaaiasltlndtllhrvvphgqsfqngyagifhfq
lwqfgewvdvvvddllpikdgklvfvhsaegnefwsallekayakvngsyealsggstse
afedftggvtewyelrkapsdlyqiilkalergsllgcsidissvldmeaitfkklvkgh
aysvtgakqvnyrgqvvslirmrnpwgevewtgawsdsssewnnvdpyerdqlrvkmedg
efwmsfrdfmreftrleicnl