PDB entry 1z92

View 1z92 on RCSB PDB site
Description: structure of interleukin-2 with its alpha receptor
Class: immune system
Keywords: Interleukin-2, interleukin-2 alpha receptor, IMMUNE SYSTEM
Deposited on 2005-03-31, released 2005-06-07
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-02-03.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.233
AEROSPACI score: 0.22 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: interleukin-2
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1z92a_
  • Chain 'B':
    Compound: Interleukin-2 receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: IL2RA
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01589 (2-End)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d1z92b1, d1z92b2, d1z92b3

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1z92A (A:)
    aptssstkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcle
    eelkpleevlnlaqsknfhlrprdlisninvivlelkgsettfmceyadetativeflnr
    witfcqsiistlt
    

    Sequence, based on observed residues (ATOM records): (download)
    >1z92A (A:)
    stkktqlqlehllldlqmilnginnyknpkltrmltfkfympkkatelkhlqcleeelkp
    leevlnlarprdlisninvivlelkgsettfmceyadetativeflnrwitfcqsiistl
    t
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1z92B (B:)
    dpelcdddppeiphatfkamaykegtmlnceckrgfrriksgslymlctgnsshsswdnq
    cqctssatrnttkqvtpqpeeqkerkttemqspmqpvdqaslpghcrepppweneateri
    yhfvvgqmvyyqcvqgyralhrgpaesvckmthgktrwtqpqlictgemetsqfpgeekp
    qaspegrpesetsclvtttdfqiqtemaatmetsiftte
    

    Sequence, based on observed residues (ATOM records): (download)
    >1z92B (B:)
    dpelcdddppeiphatfkamaykegtmlnceckrgfrriksgslymlctsswdnqcqcts
    screpppweneateriyhfvvgqmvyyqcvqgyralhrgpaesvckmthgktrwtqpqli
    ctg