PDB entry 1z7x

View 1z7x on RCSB PDB site
Description: X-ray structure of human ribonuclease inhibitor complexed with ribonuclease I
Class: Hydrolase/Hydrolase INHIBITOR
Keywords: RIBONUCLEASE-INHIBITOR COMPLEX, LEUCINE-RICH REPEAT, ENZYME-INHIBITOR COMPLEX, STRUCTURAL GENOMICS, PROTEIN STRUCTURE INITIATIVE, PSI, CESG, Center for Eukaryotic Structural Genomics, Hydrolase/Hydrolase INHIBITOR COMPLEX
Deposited on 2005-03-28, released 2005-06-21
The last revision prior to the SCOPe 2.05 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: 0.178
AEROSPACI score: 0.47 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'W':
    Compound: ribonuclease inhibitor
    Species: Homo sapiens [TaxId:9606]
    Gene: RNH, PRI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1z7xw_
  • Chain 'X':
    Compound: Ribonuclease I
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASE1, RIB1, RNS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1z7xx_
  • Chain 'Y':
    Compound: ribonuclease inhibitor
    Species: Homo sapiens [TaxId:9606]
    Gene: RNH, PRI
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1z7xy_
  • Chain 'Z':
    Compound: Ribonuclease I
    Species: Homo sapiens [TaxId:9606]
    Gene: RNASE1, RIB1, RNS1
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1z7xz_
  • Heterogens: CIT, HOH

PDB Chain Sequences:

  • Chain 'W':
    Sequence, based on SEQRES records: (download) 
    >1z7xW (W:)
msldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalae
lnlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhl
sdnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnn
dineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklg
dvgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdeg
arllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvre
lcqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlve
svrqpgclleqlvlydiywseemedrlqalekdkpslrvis

    Sequence, based on observed residues (ATOM records): (download) 
    >1z7xW (W:)
sldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalael
nlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhls
dnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnnd
ineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgd
vgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdega
rllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrel
cqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlves
vrqpgclleqlvlydiywseemedrlqalekdkpslrvis

  • Chain 'X':
    Sequence, based on SEQRES records: (download) 
    >1z7xX (X:)
mkesrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcf
qekvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvh
fdasvedst

    Sequence, based on observed residues (ATOM records): (download) 
    >1z7xX (X:)
esrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcfqe
kvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvhfd
asveds

  • Chain 'Y':
    Sequence, based on SEQRES records: (download) 
    >1z7xY (Y:)
msldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalae
lnlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhl
sdnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnn
dineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklg
dvgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdeg
arllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvre
lcqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlve
svrqpgclleqlvlydiywseemedrlqalekdkpslrvis

    Sequence, based on observed residues (ATOM records): (download) 
    >1z7xY (Y:)
sldiqsldiqceelsdarwaellpllqqcqvvrlddcgltearckdissalrvnpalael
nlrsnelgdvgvhcvlqglqtpsckiqklslqnccltgagcgvlsstlrtlptlqelhls
dnllgdaglqllceglldpqcrleklqleycslsaasceplasvlrakpdfkeltvsnnd
ineagvrvlcqglkdspcqlealklescgvtsdncrdlcgivaskaslrelalgsnklgd
vgmaelcpgllhpssrlrtlwiwecgitakgcgdlcrvlrakeslkelslagnelgdega
rllcetllepgcqleslwvkscsftaaccshfssvlaqnrfllelqisnnrledagvrel
cqglgqpgsvlrvlwladcdvsdsscsslaatllanhslreldlsnnclgdagilqlves
vrqpgclleqlvlydiywseemedrlqalekdkpslrvis

  • Chain 'Z':
    Sequence, based on SEQRES records: (download) 
    >1z7xZ (Z:)
mkesrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcf
qekvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvh
fdasvedst

    Sequence, based on observed residues (ATOM records): (download) 
    >1z7xZ (Z:)
esrakkfqrqhmdsdsspsssstycnqmmrrrnmtqgrckpvntfvheplvdvqnvcfqe
kvtckngqgncyksnssmhitdcrltngsrypncayrtspkerhiivacegspyvpvhfd
asveds