PDB entry 1z62

View 1z62 on RCSB PDB site
Description: Indirubin-3'-aminooxy-acetate inhibits glycogen phosphorylase by binding at the inhibitor and the allosteric site. Broad specificities of the two sites
Class: Transferase
Keywords: glycogenolysis, type 2 diabetes, Transferase
Deposited on 2005-03-21, released 2006-03-07
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.191
AEROSPACI score: 0.46 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Glycogen phosphorylase, muscle form
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1z62a_
  • Heterogens: PLP, IAA, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1z62A (A:)
srplsdqekrkqisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvr
dhlvgrwirtqqhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldme
eleeieedaglgngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeead
dwlrygnpwekarpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvnt
mrlwsakapndfnlkdfnvggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvv
aatlqdiirrfksskfgcrdpvrtnfdafpdkvaiqlndthpslaipelmrvlvdlerld
wdkawevtvktcaytnhtvlpealerwpvhlletllprhlqiiyeinqrflnrvaaafpg
dvdrlrrmslveegavkrinmahlciagshavngvarihseilkktifkdfyelephkfq
nktngitprrwlvlcnpglaeiiaerigeeyisdldqlrkllsyvddeafirdvakvkqe
nklkfaaylereykvhinpnslfdvqvkriheykrqllnclhvitlynrikkepnkfvvp
rtvmiggkaapgyhmakmiiklitaigdvvnhdpvvgdrlrviflenyrvslaekvipaa
dlseqistagteasgtgnmkfmlngaltigtmdganvemaeeageenffifgmrvedvdr
ldqrgynaqeyydripelrqiieqlssgffspkqpdlfkdivnmlmhhdrfkvfadyeey
vkcqervsalyknprewtrmvirniatsgkfssdrtiaqyareiwgvepsrqrlpapdek
ip

    Sequence, based on observed residues (ATOM records): (download) 
    >1z62A (A:)
qisvrglagvenvtelkknfnrhlhftlvkdrnvatprdyyfalahtvrdhlvgrwirtq
qhyyekdpkriyylslefymgrtlqntmvnlalenacdeatyqlgldmeeleeieedagl
gngglgrlaacfldsmatlglaaygygiryefgifnqkicggwqmeeaddwlrygnpwek
arpeftlpvhfygrvehtsqgakwvdtqvvlampydtpvpgyrnnvvntmrlwsakapnd
ggyiqavldrnlaenisrvlypndnffegkelrlkqeyfvvaatlqdiirrfksstnfda
fpdkvaiqlndthpslaipelmrvlvdlerldwdkawevtvktcaytnhtvlpealerwp
vhlletllprhlqiiyeinqrflnrvaaafpgdvdrlrrmslveegavkrinmahlciag
shavngvarihseilkktifkdfyelephkfqnktngitprrwlvlcnpglaeiiaerig
eeyisdldqlrkllsyvddeafirdvakvkqenklkfaaylereykvhinpnslfdvqvk
riheykrqllnclhvitlynrikkepnkfvvprtvmiggkaapgyhmakmiiklitaigd
vvnhdpvvgdrlrviflenyrvslaekvipaadlseqistagteasgtgnmkfmlngalt
igtmdganvemaeeageenffifgmrvedvdrldqrgynaqeyydripelrqiieqlssg
ffspkqpdlfkdivnmlmhhdrfkvfadyeeyvkcqervsalyknprewtrmvirniats
gkfssdrtiaqyareiwgvepsrqrlpap