PDB entry 1z57

View 1z57 on RCSB PDB site
Description: Crystal structure of human CLK1 in complex with 10Z-Hymenialdisine
Class: transferase
Keywords: protein tyrosine kinase, dual specificity, splicing, human, 10Z-Hymendialdisine, Structural Genomics, Structural Genomics Consortium, SGC, TRANSFERASE
Deposited on 2005-03-17, released 2005-04-12
The last revision prior to the SCOPe 2.08 freeze date was dated 2012-08-29, with a file datestamp of 2012-08-24.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.14
AEROSPACI score: 0.6 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Dual specificity protein kinase CLK1
    Species: Homo sapiens [TaxId:9606]
    Gene: clk1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P49759 (2-End)
      • cloning artifact (0-1)
    Domains in SCOPe 2.08: d1z57a1, d1z57a2
  • Heterogens: DBQ, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1z57A (A:)
smhlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaars
eiqvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhi
rkmayqicksvnflhsnklthtdlkpenilfvqsdyteaynpkikrdertlinpdikvvd
fgsatyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdsk
ehlammerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrackplkefmlsqdv
eherlfdliqkmleydpakritlrealkhpffdllkksi

    Sequence, based on observed residues (ATOM records): (download) 
    >1z57A (A:)
smhlicqsgdvlsaryeivdtlgegafgkvvecidhkaggrhvavkivknvdryceaars
eiqvlehlnttdpnstfrcvqmlewfehhghicivfellglstydfikengflpfrldhi
rkmayqicksvnflhsnklthtdlkpenilfvqsdyteaynrdertlinpdikvvdfgsa
tyddehhstlvstrhyrapevilalgwsqpcdvwsigcilieyylgftvfpthdskehla
mmerilgplpkhmiqktrkrkyfhhdrldwdehssagryvsrackplkefmlsqdveher
lfdliqkmleydpakritlrealkhpffdllkk