PDB entry 1z3n
View 1z3n on RCSB PDB site
Description: Human aldose reductase in complex with NADP+ and the inhibitor lidorestat at 1.04 angstrom
Class: oxidoreductase
Keywords: oxidoreductase, nadp+, lidorestat
Deposited on
2005-03-14, released
2006-03-14
The last revision prior to the SCOP 1.75 freeze date was dated
2006-03-14, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 1.04 Å
R-factor: 0.098
AEROSPACI score: 1.16
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: aldose reductase
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1z3na1 - Heterogens: NDP, 3NA, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1z3nA (A:)
gshmasrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgv
aiqeklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfk
pgkeffpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglk
ykpavnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikai
aakhnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwr
vcallsctshkdypfheef
Sequence, based on observed residues (ATOM records): (download)
>1z3nA (A:)
masrillnngakmpilglgtwksppgqvteavkvaidvgyrhidcahvyqnenevgvaiq
eklreqvvkreelfivsklwctyhekglvkgacqktlsdlkldyldlylihwptgfkpgk
effpldesgnvvpsdtnildtwaameelvdeglvkaigisnfnhlqvemilnkpglkykp
avnqiechpyltqekliqycqskgivvtaysplgspdrpwakpedpslledprikaiaak
hnkttaqvlirfpmqrnlvvipksvtperiaenfkvfdfelssqdmttllsynrnwrvca
llsctshkdypfheef