PDB entry 1ywn

View 1ywn on RCSB PDB site
Description: Vegfr2 in complex with a novel 4-amino-furo[2,3-d]pyrimidine
Class: transferase
Keywords: transferase
Deposited on 2005-02-18, released 2005-08-23
The last revision prior to the SCOP 1.73 freeze date was dated 2005-08-23, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 1.71 Å
R-factor: 0.206
AEROSPACI score: 0.52 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Vascular endothelial growth factor receptor 2
    Species: HOMO SAPIENS
    Gene: KDR, FLK1
    Database cross-references and differences (RAF-indexed):
    • Uniprot P35968 (Start-315)
      • modified residue (198)
      • modified residue (203)
    Domains in SCOP 1.73: d1ywna1
  • Heterogens: LIF, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1ywnA (A:)
mdpdelpldehcerlpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtv
avkmlkegathsehralmselkilihighhlnvvnllgactkpggplmvivefckfgnls
tylrskrnefvpykvapedlykdfltlehlicysfqvakgmeflasrkcihrdlaarnil
lseknvvkicdfglardiykdpdyvrkgdarlplkwmapetifdrvytiqsdvwsfgvll
weifslgaspypgvkideefcrrlkegtrmrapdyttpemyqtmldcwhgepsqrptfse
lvehlgnllqanaqqd

    Sequence, based on observed residues (ATOM records): (download) 
    >1ywnA (A:)
lpydaskwefprdrlklgkplgrgafgqvieadafgidktatcrtvavkmlthsehralm
selkilihighhlnvvnllgactkpggplmvivefckfgnlstylrskrnefvpfltleh
licysfqvakgmeflasrkcihrdlaarnillseknvvkicdiykdpdyvrkgdarlplk
wmapetifdrvytiqsdvwsfgvllweifslgaspypgvkideefcrrlkegtrmrapdy
ttpemyqtmldcwhgepsqrptfselvehlgnllqanaqqd