PDB entry 1yvh
View 1yvh on RCSB PDB site
Description: Crystal Structure of the c-Cbl TKB Domain in Complex with the APS pTyr-618 Phosphopeptide
Class: ligase,signaling protein,immune system
Keywords: x-ray crystallography; phosphotyrosine; adapter protein, ligase,signaling protein,immune system
Deposited on
2005-02-15, released
2005-03-08
The last revision prior to the SCOPe 2.05 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.05 Å
R-factor: 0.209
AEROSPACI score: 0.4
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: CBL E3 ubiquitin protein ligase
Species: Homo sapiens [TaxId:9606]
Gene: CBL, CBL2, RNF55
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.05: d1yvha1, d1yvha2, d1yvha3 - Chain 'B':
Compound: 13-mer fragment of SH2 and PH domain-containing adapter protein APS
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: MG, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1yvhA (A:)
gsliglmkdafqphhhhhhhlsphppgtvdkkmvekcwklmdkvvrlcqnpklalknspp
yildllpdtyqhlrtilsryegkmetlgeneyfrvfmenlmkktkqtislfkegkermye
ensqprrnltklslifshmlaelkgifpsglfqgdtfritkadaaefwrkafgektivpw
ksfrqalhevhpissgleamalkstidltcndyisvfefdiftrlfqpwssllrnwnsla
vthpgymafltydevkarlqkfihkpgsyifrlsctrlgqwaigyvtadgnilqtiphnk
plfqalidgfregfylfpdgrnqnpdltg
Sequence, based on observed residues (ATOM records): (download)
>1yvhA (A:)
pgtvdkkmvekcwklmdkvvrlcqnpklalknsppyildllpdtyqhlrtilsryegkme
tlgeneyfrvfmenlmkktkqtislfkegkermyeensqprrnltklslifshmlaelkg
ifpsglfqgdtfritkadaaefwrkafgektivpwksfrqalhevhpissgleamalkst
idltcndyisvfefdiftrlfqpwssllrnwnslavthpgymafltydevkarlqkfihk
pgsyifrlsctrlgqwaigyvtadgnilqtiphnkplfqalidgfregfylfpdgrnqnp
dltg
- Chain 'B':
No sequence available.