PDB entry 1yr2

View 1yr2 on RCSB PDB site
Description: Structural and Mechanistic Analysis of Two Prolyl Endopeptidases: Role of Inter-Domain Dynamics in Catalysis and Specificity
Class: hydrolase
Keywords: prolyl endopeptidase, mechanistic study, celiac sprue, HYDROLASE
Deposited on 2005-02-02, released 2005-03-15
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: 0.162
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: prolyl oligopeptidase
    Species: Novosphingobium capsulatum [TaxId:13688]
    Gene: ATCC
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q9ZNM8 (Start-722)
      • see remark 999 (666)
      • cloning artifact (723-734)
      • expression tag (735-737)
    Domains in SCOPe 2.06: d1yr2a1, d1yr2a2, d1yr2a3
  • Heterogens: GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1yr2A (A:)
mknrlwlamaaplalatpvafaqtpptlakdqampslppypaspqvplvedhfgekvsdp
wrwleadvrtdakvaawvqaqsaytaaylkqlperaalekrmkalidyerfglpqrrgas
vfyswnsglmnqsqllvrpadapvgtkgrvlldpntwakdgataldawaasddgrllays
vqdggsdwrtvkfvgvadgkpladelkwvkfsglawlgndallysrfaepkegqafqaln
ynqtvwlhrlgtpqsadqpvfatpelpkrghgasvssdgrwvvitssegtdpvntvhvar
vtngkigpvtalipdlkaqwdfvdgvgdqlwfvsgdgaplkkivrvdlsgstprfdtvvp
eskdnlesvgiagnrlfasyihdaksqvlafdldgkpagavslpgigsasglsgrpgdrh
aylsfssftqpatvlaldpatakttpwepvhltfdpadfrveqvfypskdgtkvpmfivr
rkdakgplptllygyggfnvaltpwfsagfmtwidsggafalanlrgggeygdawhdagr
rdkkqnvfddfiaagewliangvtprhglaieggsngglligavtnqrpdlfaaaspavg
vmdmlrfdqftagrywvddygypekeadwrvlrryspyhnvrsgvdypailvttadtddr
vvpghsfkytaalqtaaigpkphlirietraghgsgkpidkqieetadvqaflahftglt
prpwssvdklaaalehhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1yr2A (A:)
ppypaspqvplvedhfgekvsdpwrwleadvrtdakvaawvqaqsaytaaylkqlperaa
lekrmkalidyerfglpqrrgasvfyswnsglmnqsqllvrpadapvgtkgrvlldpntw
ataldawaasddgrllaysvqdggsdwrtvkfvgvadgkpladelkwvkfsglawlgnda
llysrfaeplnynqtvwlhrlgtpqsadqpvfatpelpkrghgasvssdgrwvvitsseg
tdpvntvhvarvtngkigpvtalipdlkaqwdfvdgvgdqlwfvsgdgaplkkivrvdls
gstprfdtvvpeskdnlesvgiagnrlfasyihdaksqvlafdldgkpagavslpgigsa
sglsgrpgdrhaylsfssftqpatvlaldpatakttpwepvhltfdpadfrveqvfypsk
dgtkvpmfivrrkdakgplptllygyggfnvaltpwfsagfmtwidsggafalanlrggg
eygdawhdagrrdkkqnvfddfiaagewliangvtprhglaieggsngglligavtnqrp
dlfaaaspavgvmdmlrfdqftagrywvddygypekeadwrvlrryspyhnvrsgvdypa
ilvttadtddrvvpghsfkytaalqtaaigpkphliriepidkqieetadvqaflahftg
ltprpwssvdklaaalehhh