PDB entry 1ymm

View 1ymm on RCSB PDB site
Description: TCR/HLA-DR2b/MBP-peptide complex
Class: immune system
Keywords: protein-protein complex, T cell repertoire, auto-immunity, IMMUNE SYSTEM
Deposited on 2005-01-21, released 2005-05-03
The last revision prior to the SCOPe 2.05 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-25.
Experiment type: XRAY
Resolution: 3.5 Å
R-factor: 0.274
AEROSPACI score: 0.08 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: hla class II histocompatibility antigen, dr alpha chain
    Species: Homo sapiens [TaxId:9606]
    Gene: HLA-DRA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1ymma1, d1ymma2
  • Chain 'B':
    Compound: HLA class II histocompatibility antigen, DR beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.05: d1ymmb1, d1ymmb2
  • Chain 'C':
    Compound: MBP peptide
    Database cross-references and differences (RAF-indexed):
  • Chain 'D':
    Compound: T cell receptor alpha chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • GB AAO72258
      • see remark 999 (91-94)
      • see remark 999 (99-100)
      • see remark 999 (103)
    Domains in SCOPe 2.05: d1ymmd1
  • Chain 'E':
    Compound: T-cell receptor beta chain
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P01850 (0-End)
      • engineered (12)
      • see remark 999 (97-98)
      • see remark 999 (101-103)
      • engineered (192)
    Domains in SCOPe 2.05: d1ymme1, d1ymme2
  • Heterogens: NAG

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1ymmA (A:)
    ikeehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgal
    aniavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvt
    wlrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwef
    dapsplpette
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ymmA (A:)
    keehviiqaefylnpdqsgefmfdfdgdeifhvdmakketvwrleefgrfasfeaqgala
    niavdkanleimtkrsnytpitnvppevtvltnspvelrepnvlicfidkftppvvnvtw
    lrngkpvttgvsetvflpredhlfrkfhylpflpstedvydcrvehwgldepllkhwefd
    ap
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1ymmB (B:)
    gdtrprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaey
    wnsqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsktqplqhhnllvcsvs
    gfypgsievrwflngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsv
    tspltvewrarsesaqsk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ymmB (B:)
    trprflwqpkrechffngtervrfldryfynqeesvrfdsdvgefravtelgrpdaeywn
    sqkdileqaraavdtycrhnygvvesftvqrrvqpkvtvypsllvcsvsgfypgsievrw
    flngqeekagmvstgliqngdwtfqtlvmletvprsgevytcqvehpsvtspltvewr
    

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1ymmD (D:)
    sqqgeedpqalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgr
    lrvtldtskksssllitasraadtasyfcatdttsgtykyifgtgtrlkvlaniqnpdpa
    vyqlrdskssdksvclftdfdsqtnvsqskdsdvyitdktvldmrsmdfksnsavawsnk
    sdfacanafnnsiipedtffpspessc
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ymmD (D:)
    qalsiqegenatmncsyktsinnlqwyrqnsgrglvhlilirsnerekhsgrlrvtldts
    kksssllitasraadtasyfcatdttsgtykyifgt
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1ymmE (E:)
    gavvsqhpswvisksgtsvkiecrsldfqattmfwyrqfpkqslmlmatsnegskatyeq
    gvekdkflinhasltlstltvtsahpedssfyicsardltsganneqffgpgtrltvled
    lknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqp
    lkeqpalndsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivs
    aeawgradc
    

    Sequence, based on observed residues (ATOM records): (download)
    >1ymmE (E:)
    gavvsqhpswvisksgtsvkiecrsldfqattmfwyrqfpkqslmlmatsnegskatyeq
    gvekdkflinhasltlstltvtsahpedssfyicsardltsganneqffgpgtrltvled
    lknvfppevavfepseaeishtqkatlvclatgfypdhvelswwvngkevhsgvstdpqp
    lkeqpalndsryslssrlrvsatfwqnprnhfrcqvqfyglsendewtqdrakpvtqivs
    aeawgr