PDB entry 1yk8

View 1yk8 on RCSB PDB site
Description: Cathepsin K complexed with a cyanamide-based inhibitor
Class: hydrolase
Keywords: catK, cathepsin, cysteine, protease, HYDROLASE
Deposited on 2005-01-17, released 2005-07-19
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.219
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cathepsin k
    Species: Homo sapiens [TaxId:9606]
    Gene: CTSK, CTSO, CTSO2
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1yk8a_
  • Heterogens: T2M, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1yk8A (A:)
    apdsvdyrkkgyvtpvknqgqcgscwafssvgalegqlkkktgkllnlspqnlvdcvsen
    dgcgggymtnafqyvqknrgidsedaypyvgqeescmynptgkaakcrgyreipegneka
    lkravarvgpvsvaidasltsfqfyskgvyydescnsdnlnhavlavgygiqkgnkhwii
    knswgenwgnkgyilmarnknnacgianlasfpkm
    

    Sequence, based on observed residues (ATOM records): (download)
    >1yk8A (A:)
    dsvdyrkkgyvtpvknqgqcgscwafssvgalegqlkkktgkllnlspqnlvdcvsendg
    cgggymtnafqyvqknrgidsedaypyvgqeescmynptgkaakcrgyreipegnekalk
    ravarvgpvsvaidasltsfqfyskgvyydescnsdnlnhavlavgygiqkgnkhwiikn
    swgenwgnkgyilmarnknnacgianlasfpkm