PDB entry 1yfh
View 1yfh on RCSB PDB site
Description: wt Human O6-Alkylguanine-DNA Alkyltransferase Bound To DNA Containing an Alkylated Cytosine
Class: transferase/DNA
Keywords: protein-DNA complex, TRANSFERASE/DNA COMPLEX
Deposited on
2004-12-31, released
2005-12-13
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 3.01 Å
R-factor: 0.246
AEROSPACI score: 0.18
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: methylated-DNA--protein-cysteine methyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: MGMT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1yfha1, d1yfha2 - Chain 'B':
Compound: methylated-DNA--protein-cysteine methyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: MGMT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1yfhb1, d1yfhb2 - Chain 'C':
Compound: methylated-DNA--protein-cysteine methyltransferase
Species: Homo sapiens [TaxId:9606]
Gene: MGMT
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1yfhc1, d1yfhc2 - Chain 'D':
Compound: 5'-d(*gp*tp*gp*gp*ap*tp*gp*(xcy)p*gp*tp*gp*tp*ap*gp*gp*t)-3'
Species: synthetic, synthetic
- Chain 'E':
Compound: 5'-d(*cp*cp*tp*ap*cp*ap*cp*ap*cp*ap*tp*cp*cp*ap*cp*a)-3'
Species: synthetic, synthetic
- Chain 'F':
Compound: 5'-d(*gp*tp*gp*gp*ap*tp*gp*(xcy)p*gp*tp*gp*tp*ap*gp*gp*t)-3'
Species: synthetic, synthetic
- Chain 'G':
Compound: 5'-d(*cp*cp*tp*ap*cp*ap*cp*ap*cp*ap*tp*cp*cp*ap*cp*a)-3'
Species: synthetic, synthetic
- Heterogens: ZN, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1yfhA (A:)
mdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplm
qctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaal
agnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp
Sequence, based on observed residues (ATOM records): (download)
>1yfhA (A:)
cemkrttldsplgklelsgceqglheikllgvpapaavlggpeplmqctawlnayfhqpe
aieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggam
rgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1yfhB (B:)
mdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplm
qctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaal
agnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp
Sequence, based on observed residues (ATOM records): (download)
>1yfhB (B:)
cemkrttldsplgklelsgceqglheikllgvpapaavlggpeplmqctawlnayfhqpe
aieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggam
rgnpvpilipchrvvcssgavgnysgglavkewllaheghr
- Chain 'C':
Sequence, based on SEQRES records: (download)
>1yfhC (C:)
mdkdcemkrttldsplgklelsgceqglheikllgkgtsaadavevpapaavlggpeplm
qctawlnayfhqpeaieefpvpalhhpvfqqesftrqvlwkllkvvkfgevisyqqlaal
agnpkaaravggamrgnpvpilipchrvvcssgavgnysgglavkewllaheghrlgkp
Sequence, based on observed residues (ATOM records): (download)
>1yfhC (C:)
cemkrttldsplgklelsgceqglheikllggpeplmqctawlnayfhqpeaieefpvpa
lhhpvfqqesftrqvlwkllkvvkfgevisyqqlaalagnpkaaravggamrgnpvpili
pchrvvcssgavglavkewllaheghrlg
- Chain 'D':
No sequence available.
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.
- Chain 'G':
No sequence available.