PDB entry 1yc1
View 1yc1 on RCSB PDB site
Description: Crystal Structures of human HSP90alpha complexed with dihydroxyphenylpyrazoles
Class: cell cycle
Keywords: cell-cycle, cancer, drug design
Deposited on
2004-12-21, released
2005-02-22
The last revision prior to the SCOP 1.73 freeze date was dated
2005-02-22, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.19
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Heat shock protein HSP 90-alpha
Species: HOMO SAPIENS
Gene: HSPCA, HSP90A, HSPC1
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.73: d1yc1a1 - Heterogens: 4BC, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1yc1A (A:)
mrgshhhhhhgmasmtggqqmgrdlyddddkdrwgsdqpmeeeevetfafqaeiaqlmsl
iintfysnkeiflrelisnssdaldkiryetltdpskldsgkelhinlipnkqdrtltiv
dtgigmtkadlinnlgtiaksgtkafmealqagadismigqfgvgfysaylvaekvtvit
khnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedqteyleerrikeivkkhsq
figypitlfvekerdkevsddeae
Sequence, based on observed residues (ATOM records): (download)
>1yc1A (A:)
eevetfafqaeiaqlmsliintfysnkeiflrelisnssdaldkiryetltdpskldsgk
elhinlipnkqdrtltivdtgigmtkadlinnlgtiaksgtkafmealqagadismigqf
gvgfysaylvaekvtvitkhnddeqyawessaggsftvrtdtgepmgrgtkvilhlkedq
teyleerrikeivkkhsqfigypitlfvek