PDB entry 1y8x
View 1y8x on RCSB PDB site
Description: Structural basis for recruitment of Ubc12 by an E2-binding domain in NEDD8's E1
Class: ligase
Keywords: Ubiquitin-conjugating enzyme E2 M, LIGASE
Deposited on
2004-12-13, released
2005-02-08
The last revision prior to the SCOPe 2.08 freeze date was dated
2009-02-24, with a file datestamp of
2009-02-03.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.242
AEROSPACI score: 0.28
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Ubiquitin-conjugating enzyme E2 M
Species: Homo sapiens [TaxId:9606]
Gene: UBE2M, UBC12
Database cross-references and differences (RAF-indexed):
- Uniprot P61081 (3-159)
- cloning artifact (0-2)
- modified residue (74)
- modified residue (144)
Domains in SCOPe 2.08: d1y8xa1, d1y8xa2 - Chain 'B':
Compound: ubiquitin-activating enzyme E1C
Species: Homo sapiens [TaxId:9606]
Gene: UBE1C, UBA3
Database cross-references and differences (RAF-indexed):
- Uniprot Q8TBC4
- modified residue (31)
- engineered (49)
Domains in SCOPe 2.08: d1y8xb1 - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1y8xA (A:)
gsmasaaqlriqkdinelnlpktcdisfsdpddllnfklvicpdegfyksgkfvfsfkvg
qgyphdppkvkcetmvyhpnidlegnvclnilredwkpvltinsiiyglqylflepnped
plnkeaaevlqnnrrlfeqnvqrsmrggyigstyferclk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1y8xB (B:)
gssqlpqniqfspsaklqevldyltnsaslqmkspaitatlegknrtlymqsvtsieert
rpnlsktlkelglvdgqelavadvttpqtvlfklhfts
Sequence, based on observed residues (ATOM records): (download)
>1y8xB (B:)
lpqniqfspsaklqevldyltnsaslqmkspaitatlegknrtlymqsvtsieertrpnl
sktlkelglvdgqelavadvttpqtvlfklhf