PDB entry 1y8p

View 1y8p on RCSB PDB site
Description: Crystal structure of the PDK3-L2 complex
Class: transferase
Keywords: pyruvate dehydrogenase kinase 3, lipoyl-bearing domain, protein-protein complex, TRANSFERASE
Deposited on 2004-12-13, released 2005-05-24
The last revision prior to the SCOPe 2.06 freeze date was dated 2011-10-05, with a file datestamp of 2011-09-30.
Experiment type: XRAY
Resolution: 2.63 Å
R-factor: 0.205
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3
    Species: Homo sapiens [TaxId:9606]
    Gene: PDK3
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1y8pa1, d1y8pa3
  • Chain 'B':
    Compound: Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex
    Species: Homo sapiens [TaxId:9606]
    Gene: DLAT, DLTA
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1y8pb_
  • Heterogens: MG, K, RED, ATP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1y8pA (A:)
    ggshhhhhhgmarlenlyfqgkqpvpkqierysrfspsplsikqfldfgrdnacektsym
    flrkelpvrlantmrevnllpdnllnrpsvglvqswymqsflelleyenkspedpqvldn
    flqvlikvrnrhndvvptmaqgvieykekfgfdpfistniqyfldrfytnrisfrmlinq
    htllfggdtnpvhpkhigsidptcnvadvvkdayetakmlceqyylvapeleveefnaka
    pdkpiqvvyvpshlfhmlfelfknsmratvelyedrkegypavktlvtlgkedlsikisd
    lgggvplrkidrlfnymystaprpsleptraaplagfgyglpisrlyaryfqgdlklysm
    egvgtdaviylkalssesferlpvfnksawrhykttpeaddwsnpsseprdaskykakq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1y8pA (A:)
    vpkqierysrfspsplsikqfldfgrdnacektsymflrkelpvrlantmrevnllpdnl
    lnrpsvglvqswymqsflelleyenkspedpqvldnflqvlikvrnrhndvvptmaqgvi
    eykekfgfdpfistniqyfldrfytnrisfrmlinqhtllfggdtnpvhpkhigsidptc
    nvadvvkdayetakmlceqyylvapeleveefnakapdkpiqvvyvpshlfhmlfelfkn
    smratvelyedrkegypavktlvtlgkedlsikisdlgggvplrkidrlfnymystaprp
    lagfgyglpisrlyaryfqgdlklysmegvgtdaviylkalssesferlpvfnksawrhy
    kttpeaddwsnpsseprdask
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1y8pB (B:)
    ggshhhhhhgmarlenlyfqgssypphmqvllpalsptmtmgtvqrwekkvgeklsegdl
    laeietdkatigfevqeegylakilvpegtrdvplgtplciivekeadisafadyrptev
    tdlkpqvp
    

    Sequence, based on observed residues (ATOM records): (download)
    >1y8pB (B:)
    sypphmqvllpalsptmtmgtvqrwekkvgeklsegdllaeietdkatigfevqeegyla
    kilvpegtrdvplgtplciivekeadisafadytdlk