PDB entry 1xx9

View 1xx9 on RCSB PDB site
Description: Crystal Structure of the FXIa Catalytic Domain in Complex with EcotinM84R
Class: blood clotting/hydrolase inhibitor
Keywords: FXIa; Catalytic domain; Serine protein; Ecotin
Deposited on 2004-11-04, released 2004-11-16
The last revision prior to the SCOP 1.73 freeze date was dated 2005-02-22, with a file datestamp of 2007-06-28.
Experiment type: XRAY
Resolution: 2.2 Å
R-factor: 0.235
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Coagulation factor XI
    Species: HOMO SAPIENS
    Gene: F11
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xx9a_
  • Chain 'B':
    Compound: Coagulation factor XI
    Species: HOMO SAPIENS
    Gene: F11
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xx9b_
  • Chain 'C':
    Compound: ecotin
    Species: Escherichia coli
    Gene: eco,eti
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23827 (Start-141)
      • engineered (83)
    Domains in SCOP 1.73: d1xx9c_
  • Chain 'D':
    Compound: ecotin
    Species: Escherichia coli
    Gene: eco,eti
    Database cross-references and differences (RAF-indexed):
    • Uniprot P23827 (Start-141)
      • engineered (83)
    Domains in SCOP 1.73: d1xx9d_
  • Heterogens: NAG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xx9A (A:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseikedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpiclpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqav

    Sequence, based on observed residues (ATOM records): (download) 
    >1xx9A (A:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseikedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpiclpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqa

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1xx9B (B:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseikedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpiclpskgdr
nviytdcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyregg
kdackgdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqav

    Sequence, based on observed residues (ATOM records): (download) 
    >1xx9B (B:)
ivggtasvrgewpwqvtlhttsptqrhlcggsiignqwiltaahcfygvespkilrvysg
ilnqseikedtsffgvqeiiihdqykmaesgydiallklettvnytdsqrpiclpskgyt
dcwvtgwgyrklrdkiqntlqkakiplvtneecqkryrghkithkmicagyreggkdack
gdsggplsckhnevwhlvgitswgegcaqrerpgvytnvveyvdwilektqav

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1xx9C (C:)
aesvqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggkle
nktlegwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytp
dnvdvkyrvwkaeekidnavvr

    Sequence, based on observed residues (ATOM records): (download) 
    >1xx9C (C:)
svqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggklenk
tlegwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytpdn
vdvkyrvwkaeekidnavvr

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1xx9D (D:)
aesvqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggkle
nktlegwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytp
dnvdvkyrvwkaeekidnavvr

    Sequence, based on observed residues (ATOM records): (download) 
    >1xx9D (D:)
vqplekiapypqaekgmkrqviqltpqedestlkvelligqtlevdcnlhrlggklenkt
legwgydyyvfdkvsspvstrmacpdgkkekkfvtaylgdagmlrynsklpivvytpdnv
dvkyrvwkaeekidnavvr