PDB entry 1xvp
View 1xvp on RCSB PDB site
Description: crystal structure of CAR/RXR heterodimer bound with SRC1 peptide, fatty acid and CITCO
Class: DNA binding protein
Keywords: car, rxr, citco, src1, DNA binding protein
Deposited on
2004-10-28, released
2004-12-28
The last revision prior to the SCOPe 2.01 freeze date was dated
2009-02-24, with a file datestamp of
2009-03-01.
Experiment type: XRAY
Resolution: 2.6 Å
R-factor: 0.18
AEROSPACI score: 0.31
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Retinoic acid receptor RXR-alpha
Species: Homo sapiens [TaxId:9606]
Gene: Nr1i3, Car
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1xvpa_ - Chain 'B':
Compound: Orphan nuclear receptor NR1I3
Species: Homo sapiens [TaxId:9606]
Gene: RXRA, NR2B1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1xvpb_ - Chain 'C':
Compound: Retinoic acid receptor RXR-alpha
Species: Homo sapiens [TaxId:9606]
Gene: Nr1i3, Car
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1xvpc_ - Chain 'D':
Compound: Orphan nuclear receptor NR1I3
Species: Homo sapiens [TaxId:9606]
Gene: RXRA, NR2B1
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.01: d1xvpd_ - Chain 'E':
Compound: nuclear receptor coactivator 1 isoform 1
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'F':
Compound: nuclear receptor coactivator 1 isoform 1
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'G':
Compound: nuclear receptor coactivator 1 isoform 1
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: nuclear receptor coactivator 1 isoform 1
Species: synthetic, synthetic
Database cross-references and differences (RAF-indexed):
- Heterogens: F15, CID, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1xvpA (A:)
nedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakri
phfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaif
drvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckh
kypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt
Sequence, based on observed residues (ATOM records): (download)
>1xvpA (A:)
nedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakri
phfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaif
drvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckh
kypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleap
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1xvpB (B:)
pvqlskeqeelirtllgahtrhmgtmfeqfvqfrppahlfihhqplptlapvlplvthfa
dintfmvlqvikftkdlpvfrslpiedqisllkgaaveichivlnttfclqtqnflcgpl
rytiedgarvgfqveflellfhfhgtlrklqlqepeyvllaamalfspdrpgvtqrdeid
qlqeemaltlqsyikgqqrrprdrflyakllgllaelrsineaygyqiqhiqglsammpl
lqeics
- Chain 'C':
Sequence; same for both SEQRES and ATOM records: (download)
>1xvpC (C:)
nedmpverileaelavepktetyveanmglnpsspndpvtnicqaadkqlftlvewakri
phfselplddqvillragwnelliasfshrsiavkdgillatglhvhrnsahsagvgaif
drvltelvskmrdmqmdktelgclraivlfnpdskglsnpaevealrekvyasleayckh
kypeqpgrfaklllrlpalrsiglkclehlfffkligdtpidtflmemleaphqmt
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1xvpD (D:)
pvqlskeqeelirtllgahtrhmgtmfeqfvqfrppahlfihhqplptlapvlplvthfa
dintfmvlqvikftkdlpvfrslpiedqisllkgaaveichivlnttfclqtqnflcgpl
rytiedgarvgfqveflellfhfhgtlrklqlqepeyvllaamalfspdrpgvtqrdeid
qlqeemaltlqsyikgqqrrprdrflyakllgllaelrsineaygyqiqhiqglsammpl
lqeics
- Chain 'E':
No sequence available.
- Chain 'F':
No sequence available.
- Chain 'G':
No sequence available.
- Chain 'H':
No sequence available.