PDB entry 1xrs

View 1xrs on RCSB PDB site
Description: Crystal structure of Lysine 5,6-Aminomutase in complex with PLP, cobalamin, and 5'-deoxyadenosine
Class: isomerase
Keywords: TIM barrel, Rossmann domain, PLP, Cobalamin, B12, 5'-Deoxyadenosine, Radical, mutase, Adenosylcobalamin, Conformational change
Deposited on 2004-10-15, released 2004-11-09
The last revision prior to the SCOP 1.73 freeze date was dated 2004-11-09, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.199
AEROSPACI score: 0.26 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: D-lysine 5,6-aminomutase alpha subunit
    Species: Clostridium sticklandii
    Gene: KamDE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xrsa_
  • Chain 'B':
    Compound: D-lysine 5,6-aminomutase beta subunit
    Species: Clostridium sticklandii
    Gene: KamDE
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xrsb1, d1xrsb2
  • Heterogens: B12, PLP, 5AD

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1xrsA (A:)
mesklnldfnlvekarakakaiaidtqefiekhttvtveravcrllgidgvdtdevplpn
ivvdhikennglnlgaamyianavlntgktpqeiaqaisageldltklpmkdlfevktka
lsmaketvekiknnrsiresrfeeygdksgpllyvivatgniyeditqavaaakqgadvi
avirttgqslldyvpygattegfggtyatqenfrlmrealdkvgaevgkyirlcnycsgl
cmpeiaamgaierldvmlndalygilfrdinmqrtmidqnfsriingfagviintgedny
lttadafeeahtvlasqfineqfallaglpeeqmglghafemdpelkngflyelsqaqma
reifpkaplkympptkfmtgnifkghiqdalfnmvtimtnqrihllgmltealhtpfmsd
ralsienaqyifnnmesiseeiqfkedgliqkragfvlekanelleeieqlglfdtlekg
ifggvkrpkdggkglngvvskdenyynpfvelmlnk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1xrsB (B:)
mssglysmekkefdkvldlervkpygdtmndgkvqlsftlplknnersaeaakqialkmg
leepsvvmqqsldeeftffvvygnfvqsvnyneihveavnseilsmeetdeyikenigrk
ivvvgastgtdahtvgidaimnmkgyaghygleryemidaynlgsqvanedfikkavele
advllvsqtvtqknvhiqnmthlielleaeglrdrfvllcggprinneiakelgydagfg
pgrfaddvatfavktlndrmns

    Sequence, based on observed residues (ATOM records): (download) 
    >1xrsB (B:)
kvqlsftlplknnersaeaakqialkmgleepsvvmqqsldeeftffvvygneilsmeet
deyikenigrkivvvgastgtdahtvgidaimnmkgyaghygleryemidaynlgsqvan
edfikkaveleadvllvsqtvtqknvhiqnmthlielleaeglrdrfvllcggprinnei
akelgydagfgpgrfaddvatfavktlndrmn