PDB entry 1xpu

View 1xpu on RCSB PDB site
Description: Structural mechanism of inhibition of the Rho transcription termination factor by the antibiotic 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB)
Class: transcription/RNA
Keywords: Rho transcription termination factor; 5a-(3-formylphenylsulfanyl)-dihydrobicyclomycin (FPDB); ATPgammaS, TRANSCRIPTION-RNA COMPLEX
Deposited on 2004-10-09, released 2004-11-02
The last revision prior to the SCOPe 2.08 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 3.05 Å
R-factor: 0.288
AEROSPACI score: 0.16 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rho transcription termination factor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1xpua1, d1xpua2, d1xpua3
  • Chain 'B':
    Compound: Rho transcription termination factor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1xpub1, d1xpub2, d1xpub3
  • Chain 'C':
    Compound: Rho transcription termination factor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1xpuc1, d1xpuc2, d1xpuc3
  • Chain 'D':
    Compound: Rho transcription termination factor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1xpud1, d1xpud2, d1xpud3
  • Chain 'E':
    Compound: Rho transcription termination factor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1xpue1, d1xpue2, d1xpue3
  • Chain 'F':
    Compound: Rho transcription termination factor
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1xpuf1, d1xpuf2, d1xpuf3
  • Chain 'G':
    Compound: 5'-r(*cp*up*cp*up*cp*up*cp*u)-3'
  • Chain 'H':
    Compound: 5'-r(*cp*up*cp*up*cp*up*cp*u)-3'
  • Chain 'J':
    Compound: 5'-r(*cp*up*cp*up*cp*up*cp*u)-3'
  • Chain 'K':
    Compound: 5'-r(*cp*up*cp*up*cp*up*cp*u)-3'
  • Chain 'L':
    Compound: 5'-r(*cp*up*cp*up*cp*up*cp*u)-3'
  • Chain 'M':
    Compound: 5'-r(*cp*up*cp*up*cp*up*cp*u)-3'
  • Heterogens: MG, AGS, FPD, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xpuA (A:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivapp
kagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhv
qvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrf
fgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidy
nrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1xpuA (A:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpennkilfenltplhansrlrmgstedltarvldlaspigrgqrglivappkagktm
llqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemv
iekakrlvehkkdviilldsitrlarayntvvpavltggvdanalhrpkrffgaarnvee
ggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkee
llttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmk

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1xpuB (B:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivapp
kagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhv
qvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrf
fgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidy
nrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1xpuB (B:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpennkilfenltplhansrlrmgstedltarvldlaspigrgqrglivappkagktm
llqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemv
iekakrlvehkkdviilldsitrlarayntvvpavltggvdanalhrpkrffgaarnvee
ggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkee
llttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1xpuC (C:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivapp
kagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhv
qvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrf
fgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidy
nrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1xpuC (C:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpennkilfenltplhansrlrmgstedltarvldlaspigrgqrglivappkagktm
llqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemv
iekakrlvehkkdviilldsitrlarayntvvpavltggvdanalhrpkrffgaarnvee
ggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkee
llttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmk

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1xpuD (D:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivapp
kagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhv
qvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrf
fgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidy
nrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1xpuD (D:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpennkilfenltplhansrlrmgstedltarvldlaspigrgqrglivappkagktm
llqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemv
iekakrlvehkkdviilldsitrlarayntvvpavltggvdanalhrpkrffgaarnvee
ggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkee
llttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmk

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1xpuE (E:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivapp
kagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhv
qvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrf
fgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidy
nrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1xpuE (E:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpennkilfenltplhansrlrmgstedltarvldlaspigrgqrglivappkagktm
llqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemv
iekakrlvehkkdviilldsitrlarayntvvpaltggvdanalhrpkrffgaarnveeg
gsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkeel
lttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmk

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1xpuF (F:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpenarnkilfenltplhansrlrmergngstedltarvldlaspigrgqrglivapp
kagktmllqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhv
qvaemviekakrlvehkkdviilldsitrlarayntvvpasgkvltggvdanalhrpkrf
fgaarnveeggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidy
nrsgtrkeellttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmkrs

    Sequence, based on observed residues (ATOM records): (download) 
    >1xpuF (F:)
mnltelkntpvselitlgenmglenlarmrkqdiifailkqhaksgedifgdgvleilqd
gfgflrsadssylagpddiyvspsqirrfnlrtgdtisgkirppkegeryfallkvnevn
fdkpennkilfenltplhansrlrmgstedltarvldlaspigrgqrglivappkagktm
llqniaqsiaynhpdcvlmvlliderpeevtemqrlvkgevvastfdepasrhvqvaemv
iekakrlvehkkdviilldsitrlarayntvvpavltggvdanalhrpkrffgaarnvee
ggsltiiatalidtgskmdeviyeefkgtgnmelhlsrkiaekrvfpaidynrsgtrkee
llttqeelqkmwilrkiihpmgeidameflinklamtktnddffemmk

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'J':
    No sequence available.

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    No sequence available.