PDB entry 1xlt

View 1xlt on RCSB PDB site
Description: Crystal structure of Transhydrogenase [(domain I)2:domain III] heterotrimer complex
Class: oxidoreductase
Keywords: Transhydrogenase, NAD, NADH, NADP, NADPH
Deposited on 2004-09-30, released 2005-04-05
The last revision prior to the SCOP 1.73 freeze date was dated 2005-04-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.1 Å
R-factor: 0.232
AEROSPACI score: 0.09 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: NAD(P) transhydrogenase subunit alpha part 1
    Species: Rhodospirillum rubrum
    Gene: pntAA, nntA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xlta1, d1xlta2
  • Chain 'B':
    Compound: NAD(P) transhydrogenase subunit alpha part 1
    Species: Rhodospirillum rubrum
    Gene: pntAA, nntA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xltb1, d1xltb2
  • Chain 'C':
    Compound: NAD(P) transhydrogenase subunit beta
    Species: Rhodospirillum rubrum
    Gene: pntB, nntB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59765 (3-173)
      • cloning artifact (0-2)
    Domains in SCOP 1.73: d1xltc1
  • Chain 'D':
    Compound: NAD(P) transhydrogenase subunit alpha part 1
    Species: Rhodospirillum rubrum
    Gene: pntAA, nntA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xltd1, d1xltd2
  • Chain 'E':
    Compound: NAD(P) transhydrogenase subunit alpha part 1
    Species: Rhodospirillum rubrum
    Gene: pntAA, nntA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xlte1, d1xlte2
  • Chain 'F':
    Compound: NAD(P) transhydrogenase subunit beta
    Species: Rhodospirillum rubrum
    Gene: pntB, nntB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59765 (3-173)
      • cloning artifact (1-2)
    Domains in SCOP 1.73: d1xltf1
  • Chain 'G':
    Compound: NAD(P) transhydrogenase subunit alpha part 1
    Species: Rhodospirillum rubrum
    Gene: pntAA, nntA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xltg1, d1xltg2
  • Chain 'H':
    Compound: NAD(P) transhydrogenase subunit alpha part 1
    Species: Rhodospirillum rubrum
    Gene: pntAA, nntA1
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1xlth1, d1xlth2
  • Chain 'I':
    Compound: NAD(P) transhydrogenase subunit beta
    Species: Rhodospirillum rubrum
    Gene: pntB, nntB
    Database cross-references and differences (RAF-indexed):
    • Uniprot Q59765 (3-173)
      • cloning artifact (1-2)
    Domains in SCOP 1.73: d1xlti1
  • Heterogens: SUC, NA, NAD, NDP

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1xltA (A:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpaltgqga

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltA (A:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddefrkkqaeavlkelvkt
diaittalipgkpapvliteemvtkmkpgsviidlaveaggncplsepgkivvkhgvkiv
ghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkledetvsgtcvtrdgaivhpa
ltg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1xltB (B:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpaltgqga

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltB (B:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitefrkkqaeavlkelvktdia
ittalipgkpapvliteemvtkmkpgsviidlaveaggncplsepgkivvkhgvkivght
nvpsrvaadasplfaknllnfltphvdkdtktlvmkledetvsgtcvtrdgaivhpalt

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1xltC (C:)
rhmagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvag
rmpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygm
pildvekagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1xltD (D:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpaltgqga

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltD (D:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpa

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1xltE (E:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpaltgqga

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltE (E:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitveefrkkqaeavlkelvktd
iaittalipgkpapvliteemvtkmkpgsviidlaveaggncplsepgkivvkhgvkivg
htnvpsrvaadasplfaknllnfltphvdkdtktlvmkledetvsgtcvtrdgaivhpa

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1xltF (F:)
rhmagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvag
rmpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygm
pildvekagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltF (F:)
hmagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvagr
mpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygmp
ildvekagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn

  • Chain 'G':
    Sequence, based on SEQRES records: (download) 
    >1xltG (G:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpaltgqga

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltG (G:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvdgeefrkkqaeavlkelvk
tdiaittalipgkpapvliteemvtkmkpgsviidlaveaggncplsepgkivvkhgvki
vghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkledetvsgtcvtrdgaivhp
altg

  • Chain 'H':
    Sequence, based on SEQRES records: (download) 
    >1xltH (H:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfitvddeamktaetaggyakemg
eefrkkqaeavlkelvktdiaittalipgkpapvliteemvtkmkpgsviidlaveaggn
cplsepgkivvkhgvkivghtnvpsrvaadasplfaknllnfltphvdkdtktlvmkled
etvsgtcvtrdgaivhpaltgqga

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltH (H:)
mkiaipkerrpgedrvaispevvkklvglgfeviveqgagvgasitddaltaagatiast
aaqalsqadvvwkvqrpmtaeegtdevalikegavlmchlgaltnrpvvealtkrkitay
amelmprisraqsmdilssqsnlagyravidgayefarafpmmmtaagtvpparvlvfgv
gvaglqaiatakrlgavvmatdvraatkeqveslggkfiteefrkkqaeavlkelvktdi
aittalipgkpapvliteemvtkmkpgsviidlaveaggncplsepgkivvkhgvkivgh
tnvpsrvaadasplfaknllnfltphvdkdtktlvmkledetvsgtcvtrdgaivhp

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1xltI (I:)
rhmagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvag
rmpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygm
pildvekagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn

    Sequence, based on observed residues (ATOM records): (download) 
    >1xltI (I:)
hmagsaedaafimknaskviivpgygmavaqaqhalremadvlkkegvevsyaihpvagr
mpghmnvllaeanvpydevfeleeinssfqtadvafvigandvtnpaaktdpsspiygmp
ildvekagtvlfikrsmasgyagvenelffrnntmmlfgdakkmteqivqamn