PDB entry 1xkb

View 1xkb on RCSB PDB site
Description: factor xa complexed with a synthetic inhibitor fx-2212a,(2s)-(3'-amidino-3-biphenylyl)-5-(4-pyridylamino)pentanoic acid
Class: blood coagulation factor
Keywords: blood coagulation factor, serine proteinase, epidermal growth factor like domain
Deposited on 1998-03-19, released 1999-03-23
The last revision prior to the SCOPe 2.07 freeze date was dated 2012-06-20, with a file datestamp of 2012-06-15.
Experiment type: XRAY
Resolution: 2.4 Å
R-factor: 0.206
AEROSPACI score: 0.29 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: blood coagulation factor xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742
      • modified residue (18)
    Domains in SCOPe 2.07: d1xkba1, d1xkba2
  • Chain 'B':
    Compound: blood coagulation factor xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P00742 (Start-94)
      • modified residue (18)
    Domains in SCOPe 2.07: d1xkbb1, d1xkbb2
  • Chain 'C':
    Compound: blood coagulation factor xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1xkbc_
  • Chain 'D':
    Compound: blood coagulation factor xa
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1xkbd_
  • Heterogens: CA, 4PP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1xkbA (A:)
    kdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeq
    nsvvcscargytladngkaciptgpypcgkqtler
    

    Sequence, based on observed residues (ATOM records): (download)
    >1xkbA (A:)
    dqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeqnsv
    vcscargytladngkaciptgpypcgkqtle
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1xkbB (B:)
    kdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeq
    nsvvcscargytladngkaciptgpypcgkqtler
    

    Sequence, based on observed residues (ATOM records): (download)
    >1xkbB (B:)
    cetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeqnsvvc
    scargytladngkaciptgpypcgkqtler
    

  • Chain 'C':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1xkbC (C:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1xkbD (D:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmktr
    

    Sequence, based on observed residues (ATOM records): (download)
    >1xkbD (D:)
    ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
    qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
    tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
    cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmkt