PDB entry 1xbc
View 1xbc on RCSB PDB site
Description: Crystal structure of the syk tyrosine kinase domain with Staurosporin
Class: Transferase
Keywords: staurosporine, SYK, spleen typrosine kinase, active conformation, structural genomics, Structural GenomiX
Deposited on
2004-08-30, released
2004-11-02
The last revision prior to the SCOP 1.75 freeze date was dated
2005-03-22, with a file datestamp of
2007-06-04.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.246
AEROSPACI score: 0.42
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Tyrosine-protein kinase SYK
Species: HOMO SAPIENS
Gene: SYK
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1xbca_ - Heterogens: STU, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1xbcA (A:)
maleeirpkevyldrklltledkelgsgnfgtvkkgyyqmkkvvktvavkilkneandpa
lkdellaeanvmqqldnpyivrmigiceaeswmlvmemaelgplnkylqqnrhvkdknii
elvhqvsmgmkyleesnfvhrdlaarnvllvtqhyakisdfglskalradenyykaqthg
kwpvkwyapecinyykfssksdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermg
cpagcpremydlmnlcwtydvenrpgfaavelrlrnyyydvvneghhhhhh
Sequence, based on observed residues (ATOM records): (download)
>1xbcA (A:)
vyldrklltledkelgsgnfgtvkkgyyqmkkvvktvavkilpalkdellaeanvmqqld
npyivrmigiceaeswmlvmemaelgplnkylqqnrhvkdkniielvhqvsmgmkylees
nfvhrdlaarnvllvtqhyakisdfglskalradenyykaqthgkwpvkwyapecinyyk
fssksdvwsfgvlmweafsygqkpyrgmkgsevtamlekgermgcpagcpremydlmnlc
wtydvenrpgfaavelrlrnyyydvvne