PDB entry 1x8v

View 1x8v on RCSB PDB site
Description: Estriol-bound and ligand-free structures of sterol 14alpha-demethylase (CYP51)
Class: oxidoreductase
Keywords: alpha-beta, heme co-factor, protein-estriol complex, OXIDOREDUCTASE
Deposited on 2004-08-18, released 2004-11-23
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.55 Å
R-factor: 0.206
AEROSPACI score: 0.59 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: cytochrome p450 51
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: cyp51
    Database cross-references and differences (RAF-indexed):
    • Uniprot P0A512
      • engineered (36)
      • engineered (441)
    Domains in SCOPe 2.06: d1x8va_
  • Heterogens: HEM, ESL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1x8vA (A:)
msavalprvsgghdehghleefrtdpiglmqrvrdelgdvgtfqlagkqvvllsgshane
fffragdddldqakaypfmtpifgegvvfdasperrkemlhnaalrgeqmkghaatiedq
vrrmiadwgeageidlldffaeltiytssacligkkfrdqldgrfaklyhelergtdpla
yvdpylpiesfrrrdearnglvalvadimngrianpptdksdrdmldvliavkaetgtpr
fsadeitgmfismmfaghhtssgtaswtlielmrhrdayaavideldelygdgrsvsfha
lrqipqlenvlketlrlhppliilmrvakgefevqghrihegdlvaaspaisnripedfp
dphdfvparyeqprqedllnrwtwipfgagrhrcvgaafaimqikaifsvllreyefema
qppesyrndhskmvvqlaqpaavryrrrtgvhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1x8vA (A:)
savalprvsgghdehghleefrtdpiglmqrvrdelgdvgtfqlagkqvvllsgshanef
ffragdddldqakaypfmtpifgrrkemlhnaalrgeqmkghaatiedqvrrmiadwgea
geidlldffaeltiytssacligkkfrdqldgrfaklyhelergtdplayvdpylpiesf
rrrdearnglvalvadimngrianprdmldvliavkatprfsadeitgmfismmfaghht
ssgtaswtlielmrhrdayaavideldelygdgrsvsfhalrqipqlenvlketlrlhpp
liilmrvakgefevqghrihegdlvaaspaisnripedfpdphdfvparyeqprqedlln
rwtwipfgagrhrcvgaafaimqikaifsvllreyefemaqppesyrndhskmvvqlaqp
aavryrrrt