PDB entry 1x7t
View 1x7t on RCSB PDB site
Description: Structure of TTR R104H: a non-amyloidogenic variant with protective clinical effects
Class: transport protein
Keywords: Transthyretin, Familial Amyloidotic Polyneuropathy, Amyloid, TRANSPORT PROTEIN
Deposited on
2004-08-16, released
2005-03-22
The last revision prior to the SCOPe 2.06 freeze date was dated
2011-07-13, with a file datestamp of
2011-05-08.
Experiment type: XRAY
Resolution: 1.6 Å
R-factor: 0.201
AEROSPACI score: 0.55
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1x7ta_ - Chain 'B':
Compound: Transthyretin
Species: Homo sapiens [TaxId:9606]
Gene: TTR, PALB
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.06: d1x7tb_ - Heterogens: HOH
PDB Chain Sequences:
- Chain 'A':
Sequence, based on SEQRES records: (download)
>1x7tA (A:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprhytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>1x7tA (A:)
kcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegi
ykveidtksywkalispfhehaevvftandsgprhytiaallspysysttavvtnp
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1x7tB (B:)
gptgtgeskcplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltt
eeefvegiykveidtksywkalgispfhehaevvftandsgprhytiaallspysystta
vvtnpke
Sequence, based on observed residues (ATOM records): (download)
>1x7tB (B:)
cplmvkvldavrgspainvavhvfrkaaddtwepfasgktsesgelhgltteeefvegiy
kveidtksywkalgispfhehaevvftandsprhytiaallspysysttavvt