PDB entry 1x7j

View 1x7j on RCSB PDB site
Description: crystal structure of estrogen receptor beta complexed with genistein
Class: transcription
Keywords: estrogen receptor, estrogen receptor beta, er-beta, er, estrogen, nuclear receptor, transcription factor, agonist
Deposited on 2004-08-14, released 2005-03-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.232
AEROSPACI score: 0.36 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor beta
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR2, NR3A2, ESTRB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1x7ja_
  • Chain 'B':
    Compound: Estrogen receptor beta
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR2, NR3A2, ESTRB
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1x7jb_
  • Chain 'C':
    Compound: steroid receptor coactivator-1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1X7J (Start-12)
  • Chain 'D':
    Compound: steroid receptor coactivator-1
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1X7J (Start-12)
  • Heterogens: GEN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1x7jA (A:)
dalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfv
elslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdml
lattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvwv
iaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlnahvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1x7jA (A:)
lspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfvel
slfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmlla
ttsrfrelklqhkeylcvkamillnssmdssrklahllnavtdalvwviaksgissqqqs
mrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlna

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1x7jB (B:)
dalspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfv
elslfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdml
lattsrfrelklqhkeylcvkamillnssmyplvtatqdadssrklahllnavtdalvwv
iaksgissqqqsmrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlnahvl

    Sequence, based on observed residues (ATOM records): (download) 
    >1x7jB (B:)
lspeqlvltlleaepphvlisrpsapfteasmmmsltkladkelvhmiswakkipgfvel
slfdqvrllescwmevlmmglmwrsidhpgklifapdlvldrdegkcvegileifdmlla
ttsrfrelklqhkeylcvkamillnssmdssrklahllnavtdalvwviaksgissqqqs
mrlanllmllshvrhasnkgmehllnmkcknvvpvydlllemlna

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.