PDB entry 1x7e

View 1x7e on RCSB PDB site
Description: crystal structure of estrogen receptor alpha complexed with way-244
Class: transcription
Keywords: estrogen receptor, estrogen receptor beta, er-beta, er, estrogen receptor alpha, er-alpha, estrogen, nuclear recept transcription factor, agonist
Deposited on 2004-08-13, released 2005-03-01
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.219
AEROSPACI score: 0.25 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Estrogen receptor 1 (alpha)
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, NR3A1, ESR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1x7ea_
  • Chain 'B':
    Compound: Estrogen receptor 1 (alpha)
    Species: Homo sapiens [TaxId:9606]
    Gene: ESR1, NR3A1, ESR
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1x7eb_
  • Chain 'C':
    Compound: steroid receptor coactivator-3
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1X7E
  • Chain 'D':
    Compound: steroid receptor coactivator-3
    Species: synthetic, synthetic
    Database cross-references and differences (RAF-indexed):
    • PDB 1X7E
  • Heterogens: 244, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1x7eA (A:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpvkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahrl

    Sequence, based on observed residues (ATOM records): (download) 
    >1x7eA (A:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpvkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfleekdhihrvldkitdtlihlma
kagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahrl

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1x7eB (B:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpvkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytflsstlksleekdhihrvldkitd
tlihlmakagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydllleml
dahrl

    Sequence, based on observed residues (ATOM records): (download) 
    >1x7eB (B:)
slalsltadqmvsalldaeppilyseydptrpfseasmmglltnladrelvhminwakrv
pgfvdltlhdqvhllecawleilmiglvwrsmehpvkllfapnllldrnqgkcvegmvei
fdmllatssrfrmmnlqgeefvclksiillnsgvytfleekdhihrvldkitdtlihlma
kagltlqqqhqrlaqlllilshirhmsnkgmehlysmkcknvvplydlllemldahrl

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.