PDB entry 1x74

View 1x74 on RCSB PDB site
Description: Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis- mutational and structural characterization of the fold and active site
Class: isomerase
Keywords: Alpha-methylacyl-CoA racemase, racemase, CoA transferase, Coenzyme A
Deposited on 2004-08-13, released 2005-01-18
The last revision prior to the SCOP 1.73 freeze date was dated 2005-04-05, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: 0.162
AEROSPACI score: 0.54 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1x74a1
  • Chain 'B':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1x74b1
  • Chain 'C':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1x74c1
  • Chain 'D':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1x74d1
  • Heterogens: PO4, GOL, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1x74A (A:)
magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1x74A (A:)
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1x74B (B:)
magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1x74B (B:)
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1x74C (C:)
magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1x74C (C:)
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1x74D (D:)
magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg

    Sequence, based on observed residues (ATOM records): (download) 
    >1x74D (D:)
agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg