PDB entry 1x74

View 1x74 on RCSB PDB site
Description: Alpha-methylacyl-CoA racemase from Mycobacterium tuberculosis- mutational and structural characterization of the fold and active site
Class: isomerase
Keywords: Alpha-methylacyl-CoA racemase, racemase, CoA transferase, Coenzyme A, ISOMERASE
Deposited on 2004-08-13, released 2005-01-18
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-11, with a file datestamp of 2017-10-06.
Experiment type: XRAY
Resolution: 1.79 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1x74a1
  • Chain 'B':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1x74b_
  • Chain 'C':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1x74c_
  • Chain 'D':
    Compound: 2-methylacyl-CoA racemase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1x74d_
  • Heterogens: GOL, PO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1x74A (A:)
    magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
    lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
    sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
    gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
    epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
    vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

    Sequence, based on observed residues (ATOM records): (download)
    >1x74A (A:)
    agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
    lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
    dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
    amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
    amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
    vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1x74B (B:)
    magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
    lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
    sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
    gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
    epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
    vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

    Sequence, based on observed residues (ATOM records): (download)
    >1x74B (B:)
    agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
    lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
    dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
    amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
    amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
    vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1x74C (C:)
    magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
    lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
    sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
    gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
    epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
    vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

    Sequence, based on observed residues (ATOM records): (download)
    >1x74C (C:)
    agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
    lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
    dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
    amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
    amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
    vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1x74D (D:)
    magplsglrvvelagigpgphaamilgdlgadvvridrpssvdgisrdamlrnrrivtad
    lksdqglelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgpr
    sqqaghdinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgk
    gqvvdaamvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgai
    epqfyaamlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtp
    vlafgevhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg
    

    Sequence, based on observed residues (ATOM records): (download)
    >1x74D (D:)
    agplsglrvvelagigpgphaamilgdlgadvvridrpisrdamlrnrrivtadlksdqg
    lelalkliakadvliegyrpgvterlglgpeecakvndrliyarmtgwgqtgprsqqagh
    dinyislngilhaigrgderpvpplnlvgdfgggsmfllvgilaalwerqssgkgqvvda
    amvdgssvliqmmwamratgmwtdtrganmldggapyydtyecadgryvavgaiepqfya
    amlaglgldaaelppqndrarwpelrallteafashdrdhwgavfansdacvtpvlafge
    vhnephiierntfyeanggwqpmpaprfsrtassqprppaatidieavltdwdg