PDB entry 1wua

View 1wua on RCSB PDB site
Description: The structure of Aplyronine A-actin complex
Class: structural protein
Keywords: aplyronine A, macrolide, potent antitumor effect, marine sponge, STRUCTURAL PROTEIN
Deposited on 2004-12-03, released 2006-02-14
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.45 Å
R-factor: 0.153
AEROSPACI score: 0.69 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Actin, alpha skeletal muscle
    Species: Oryctolagus cuniculus [TaxId:9986]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P68135
      • modified residue (72)
    Domains in SCOPe 2.07: d1wuaa1, d1wuaa2
  • Heterogens: CA, ATP, AP8, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1wuaA (A:)
    dedettalvcdngsglvkagfagddapravfpsivgrprhqgvmvgmgqkdsyvgdeaqs
    krgiltlkypiehgiitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmt
    qimfetfnvpamyvaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldl
    agrdltdylmkiltergysfvttaereivrdikeklcyvaldfenemataassssleksy
    elpdgqvitignerfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvms
    ggttmypgiadrmqkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkq
    eydeagpsivhrkcf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1wuaA (A:)
    ttalvcdngsglvkagfagddapravfpsivgrprhqdsyvgdeaqskrgiltlkypieh
    giitnwddmekiwhhtfynelrvapeehptllteaplnpkanrekmtqimfetfnvpamy
    vaiqavlslyasgrttgivldsgdgvthnvpiyegyalphaimrldlagrdltdylmkil
    tergysfvttaereivrdikeklcyvaldfenemataassssleksyelpdgqvitigne
    rfrcpetlfqpsfigmesagihettynsimkcdidirkdlyannvmsggttmypgiadrm
    qkeitalapstmkikiiapperkysvwiggsilaslstfqqmwitkqeydeagpsivh