PDB entry 1wu1
View 1wu1 on RCSB PDB site
Description: Factor Xa in complex with the inhibitor 4-[(5-chloroindol-2-yl)sulfonyl]-2-(2-methylpropyl)-1-[[5-(pyridin-4-yl) pyrimidin-2-yl]carbonyl]piperazine
Class: hydrolase
Keywords: glycoprotein, hydrolase, serine protease, plasma, blood coagulation factor, protein inhibitor complex, calcium-binding
Deposited on
2004-11-29, released
2005-11-29
The last revision prior to the SCOPe 2.08 freeze date was dated
2012-06-20, with a file datestamp of
2012-06-15.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.191
AEROSPACI score: 0.35
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: coagulation factor x, heavy chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1wu1a_ - Chain 'B':
Compound: coagulation factor x, light chain
Species: Homo sapiens [TaxId:9606]
Database cross-references and differences (RAF-indexed):
Domains in SCOPe 2.08: d1wu1b_ - Heterogens: CA, D91, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1wu1A (A:)
ivggqeckdgecpwqallineenegfcggtilsefyiltaahclyqakrfkvrvgdrnte
qeeggeavhevevvikhnrftketydfdiavlrlktpitfrmnvapaclperdwaestlm
tqktgivsgfgrthekgrqstrlkmlevpyvdrnscklsssfiitqnmfcagydtkqeda
cqgdsggphvtrfkdtyfvtgivswgegcarkgkygiytkvtaflkwidrsmk
- Chain 'B':
Sequence, based on SEQRES records: (download)
>1wu1B (B:)
kdgdqcetspcqnqgkckdglgeytctclegfegkncelftrklcsldngdcdqfcheeq
nsvvcscargytladngkaciptgpypcgkqtler
Sequence, based on observed residues (ATOM records): (download)
>1wu1B (B:)
trklcsldngdcdqfcheeqnsvvcscargytladngkaciptgpypcgkqtle