PDB entry 1wk8

View 1wk8 on RCSB PDB site
Description: Isoleucyl-tRNA synthetase editing domain complexed with the pre-transfer editing substrate analogue, Val-AMS
Class: ligase
Keywords: editing, cp1, isoleucyl-trna synthetase, fidelity, thermus thermophilus, translation, amino acid, Structural Genomics, RIKEN Structural Genomics/Proteomics Initiative, RSGI, NPPSFA, National Project on Protein Structural and Functional Analyses, LIGASE
Deposited on 2004-05-30, released 2005-09-27
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.7 Å
R-factor: 0.206
AEROSPACI score: 0.5 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: isoleucyl-tRNA synthetase
    Species: Thermus thermophilus [TaxId:274]
    Gene: iles
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56690
      • see remark 999 (79)
    Domains in SCOPe 2.08: d1wk8a_
  • Chain 'B':
    Compound: isoleucyl-tRNA synthetase
    Species: Thermus thermophilus [TaxId:274]
    Gene: iles
    Database cross-references and differences (RAF-indexed):
    • Uniprot P56690 (Start-193)
      • see remark 999 (79)
    Domains in SCOPe 2.08: d1wk8b_
  • Heterogens: VMS, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1wk8A (A:)
mgykeiqdpsvyvrfplkepkklglekaslliwtttpwtlpgnvaaavhpeytyaafqvg
dealileeglgrkllgegtpvlktfpgkaleglpytppypqalekgyfvvladyvsqedg
tgivhqapafgaedletarvyglpllktvdeegkllvepfkglyfreanrailrdlrgrg
llfkeesylhsyph

    Sequence, based on observed residues (ATOM records): (download) 
    >1wk8A (A:)
qdpsvyvrfplkepkklglekaslliwtttpwtlpgnvaaavhpeytyaafqvgdealil
eeglgrkllgegtpvlktfpgkaleglpytppypqalekgyfvvladyvsqedgtgivhq
apafgaedletarvyglpllktvdeegkllvepfkglyfreanrailrdlrgrgllfkee
sy

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1wk8B (B:)
mgykeiqdpsvyvrfplkepkklglekaslliwtttpwtlpgnvaaavhpeytyaafqvg
dealileeglgrkllgegtpvlktfpgkaleglpytppypqalekgyfvvladyvsqedg
tgivhqapafgaedletarvyglpllktvdeegkllvepfkglyfreanrailrdlrgrg
llfkeesylhsyph

    Sequence, based on observed residues (ATOM records): (download) 
    >1wk8B (B:)
dpsvyvrfplkepkklglekaslliwtttpwtlpgnvaaavhpeytyaafqvgdealile
eglgrkllgegtpvlktfpgkaleglpytppypqalekgyfvvladyvsqedgtgivhqa
pafgaedletarvyglpllktvdeegkllvepfkglyfreanrailrdlrgrgllfkees
ylhsyph