PDB entry 1we2

View 1we2 on RCSB PDB site
Description: Crystal structure of shikimate kinase from mycobacterium tuberculosis in complex with MGADP and shikimic acid
Class: transferase
Keywords: shikimate pathway, shikimate kinase, x-ray crystallography, synchrotron, drug design, transferase
Deposited on 2004-05-22, released 2005-05-17
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.207
AEROSPACI score: 0.34 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Shikimate kinase
    Species: Mycobacterium tuberculosis [TaxId:1773]
    Gene: AroK
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1we2a_
  • Heterogens: MG, CL, ADP, DHK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1we2A (A:)
mapkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrri
eedvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrpll
agpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrlqvpspseaat

    Sequence, based on observed residues (ATOM records): (download) 
    >1we2A (A:)
apkavlvglpgsgkstigrrlakalgvglldtdvaieqrtgrsiadifatdgeqefrrie
edvvraaladhdgvlslgggavtspgvraalaghtvvyleisaaegvrrtggntvrplla
gpdraekyralmakraplyrrvatmrvdtnrrnpgavvrhilsrl