PDB entry 1wa5

View 1wa5 on RCSB PDB site
Description: crystal structure of the exportin cse1p complexed with its cargo (kap60p) and rangtp
Class: nuclear transport
Keywords: nuclear transport/complex, nuclear transport, exportin, importin alpha, ran gtpase, protein transport
Deposited on 2004-10-23, released 2004-12-13
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2 Å
R-factor: 0.2344
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: GTP-binding nuclear protein ran
    Species: CANIS FAMILIARIS [TaxId:9615]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1wa5a_
  • Chain 'B':
    Compound: importin alpha subunit
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1wa5b_
  • Chain 'C':
    Compound: importin alpha re-exporter
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1wa5c_
  • Heterogens: GTP, MG, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1wa5A (A:)
maaqgepqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpik
fnvwdtagqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlc
gnkvdikdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlef

    Sequence, based on observed residues (ATOM records): (download) 
    >1wa5A (A:)
pqvqfklvlvgdggtgkttfvkrhltgefekkyvatlgvevhplvfhtnrgpikfnvwdt
agqekfgglrdgyyiqaqcaiimfdvtsrvtyknvpnwhrdlvrvcenipivlcgnkvdi
kdrkvkaksivfhrkknlqyydisaksnynfekpflwlarkligdpnlef

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1wa5B (B:)
mdngtdsstskfvpeyrrtnfknkgrfsadelrrrrdtqqvelrkakrdealakrrnfip
ptdgadsdeedessvsadqqfysqlqqelpqmtqqlnsddmqeqlsatvkfrqilsrehr
ppidvviqagvvprlvefmrenqpemlqleaawaltniasgtsaqtkvvvdadavplfiq
llytgsvevkeqaiwalgnvagdstdyrdyvlqcnamepilglfnsnkpslirtatwtls
nlcrgkkpqpdwsvvsqalptlakliysmdtetlvdacwaisylsdgpqeaiqavidvri
pkrlvellshestlvqtpalravgnivtgndlqtqvvinagvlpalrlllsspkenikke
acwtisnitagnteqiqavidanlipplvkllevaeyktkkeacwaisnassgglqrpdi
irylvsqgcikplcdlleiadnriievtldalenilkmgeadkearglninenadfieka
ggmekifncqqnendkiyekaykiietyfgeeedavdetmapqnagntfg

    Sequence, based on observed residues (ATOM records): (download) 
    >1wa5B (B:)
fvpeyrrtelrrrrdtqqvelrkakrdealakrrnfqelpqmtqqlnsddmqeqlsatvk
frqilsrehrppidvviqagvvprlvefmrenqpemlqleaawaltniasgtsaqtkvvv
dadavplfiqllytgsvevkeqaiwalgnvagdstdyrdyvlqcnamepilglfnsnkps
lirtatwtlsnlcrgkkpqpdwsvvsqalptlakliysmdtetlvdacwaisylsdgpqe
aiqavidvripkrlvellshestlvqtpalravgnivtgndlqtqvvinagvlpalrlll
sspkenikkeacwtisnitagnteqiqavidanlipplvkllevaeyktkkeacwaisna
ssgglqrpdiirylvsqgcikplcdlleiadnriievtldalenilkmgeadkearglni
nenadfiekaggmekifncqqnendkiyekaykiietyfgeeed

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1wa5C (C:)
msdletvakflaesviastaktsernlrqletqdgfgltllhviastnlplstrlagalf
fknfikrkwvdengnhllpannvelikkeivplmislpnnlqvqigeaissiadsdfpdr
wptllsdlasrlsnddmvtnkgvltvahsifkrwrplfrsdelfleiklvldvftapfln
llktvdeqitanennkaslnilfdvllvliklyydfncqdipeffedniqvgmgifhkyl
sysnplledpdetehasvlikvkssiqelvqlyttryedvfgpminefiqitwnlltsis
nqpkydilvskslsfltavtripkyfeifnnesamnniteqiilpnvtlreedvelfedd
pieyirrdlegsdtdtrrractdflkelkeknevlvtniflahmkgfvdqymsdpsknwk
fkdlyiylftalaingnitnagvsstnnllnvvdfftkeiapdltsnniphiilrvdaik
yiytfrnqltkaqlielmpilatflqtdeyvvytyaaitiekiltiresntspafifhke
disnsteillknlialilkhgsspeklaeneflmrsifrvlqtsedsiqplfpqllaqfi
eivtimaknpsnprfthytfesigailnytqrqnlpllvdsmmptfltvfsediqefipy
vfqiiafvveqsatipesikplaqpllapnvwelkgnipavtrllksfiktdssifpdlv
pvlgifqrliaskayevhgfdllehimllidmnrlrpyikqiavlllqrlqnskteryvk
kltvffglisnklgsdflihfidevqdglfqqiwgnfiittlptignlldrkialigvln
mvingqffqskyptlisstmnsiietassqsianlkndyvdldnleeistfgshfsklvs
isekpfdplpeidvnngvrlyvaealnkynaisgntflntilpqltqenqvklnqllvgn

    Sequence, based on observed residues (ATOM records): (download) 
    >1wa5C (C:)
msdletvakflaesviastaktsernlrqletqdgfgltllhviastnlplstrlagalf
fknfikrkwvdengnhllpannvelikkeivplmislpnnlqvqigeaissiadsdfpdr
wptllsdlasrlsnddmvtnkgvltvahsifkrwrplfrsdelfleiklvldvftapfln
llktvdeqitanekaslnilfdvllvliklyydfncqdipeffedniqvgmgifhkylsy
snpllehasvlikvkssiqelvqlyttryedvfgpminefiqitwnlltsisnqpkydil
vskslsfltavtripkyfeifnnesamnniteqiilpnvtlreedvelfeddpieyirrd
legtrrractdflkelkeknevlvtniflahmkgfvdqymsnwkfkdlyiylftalaing
nitnagvsstnnllnvvdfftkeiapdltsnniphiilrvdaikyiytfrnqltkaqlie
lmpilatflqtdeyvvytyaaitiekiltiresntspafifhkedisnsteillknlial
ilkhgsspeklaeneflmrsifrvlqtsedsiqplfpqllaqfieivtimaknpsnprft
hytfesigailnytqrqnlpllvdsmmptfltvfsediqefipyvfqiiafvveqsatip
esikplaqpllapnvwelkgnipavtrllksfiktdssifpdlvpvlgifqrliaskaye
vhgfdllehimllidmnrlrpyikqiavlllqrlqnskteryvkkltvffglisnklgsd
flihfidevqdglfqqiwgnfiittlptignlldrkialigvlnmvingqffqskyptli
sstmnsiietassqsianlkndyveeistfgshfsklvsisekpfdplpeidvnngvrly
vaealnkynaisgntflntilpqltqenqvklnqllvg