PDB entry 1w98

View 1w98 on RCSB PDB site
Description: the structural basis of cdk2 activation by cyclin e
Class: transferase
Keywords: cell cycle, transferase
Deposited on 2004-10-07, released 2005-02-02
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-31.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.185
AEROSPACI score: 0.4 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Cell division protein kinase 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P24941 (1-297)
      • expression tag (0)
    Domains in SCOPe 2.07: d1w98a2, d1w98a3
  • Chain 'B':
    Compound: g1/s-specific cyclin e1
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1w98b1, d1w98b2
  • Heterogens: HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1w98A (A:)
    smenfqkvekigegtygvvykarnkltgevvalkkirldtetegvpstaireisllkeln
    hpnivklldvihtenklylvfeflhqdlkkfmdasaltgiplpliksylfqllqglafch
    shrvlhrdlkpqnllintegaikladfglarafgvpvrtythevvtlwyrapeillgcky
    ystavdiwslgcifaemvtrralfpgdseidqlfrifrtlgtpdevvwpgvtsmpdykps
    fpkwarqdfskvvppldedgrsllsqmlhydpnkrisakaalahpffqdvtkpvphlr
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1w98B (B:)
    iiapsrgsplpvlswanreevwkimlnkektylrdqhfleqhpllqpkmrailldwlmev
    cevyklhretfylaqdffdrymatqenvvktllqligisslfiaakleeiyppklhqfay
    vtdgacsgdeiltmelmimkalkwrlspltivswlnvymqvaylndlhevllpqypqqif
    iqiaelldlcvldvdclefpygilaasalyhfssselmqkvsgyqwcdiencvkwmvpfa
    mviretgssklkhfrgvadedahniqthrdsldlldkarakka
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w98B (B:)
    splpvlswanreevwkimlnkektylrdqhfleqhpllqpkmrailldwlmevcevyklh
    retfylaqdffdrymatqenvvktllqligisslfiaakleeiyppklhqfayvtdgacs
    gdeiltmelmimkalkwrlspltivswlnvymqvaylndlhevllpqypqqifiqiaell
    dlcvldvdclefpygilaasalyhfssselmqkvsgyqwcdiencvkwmvpfamviretg
    ssklkhfrgvadedahniqthrdsldlldk