PDB entry 1w72
View 1w72 on RCSB PDB site
Description: crystal structure of hla-a1:mage-a1 in complex with fab-hyb3
Class: complex, hla/fab fragment
Keywords: hla, human leucocyte antigen, mage, peptide-specific fab, tcr-like binding, MHC-I
Deposited on
2004-08-27, released
2004-11-09
The last revision prior to the SCOP 1.75 freeze date was dated
2005-01-27, with a file datestamp of
2007-06-28.
Experiment type: XRAY
Resolution: 2.15 Å
R-factor: 0.186
AEROSPACI score: 0.53
(click here for full SPACI score report)
Chains and heterogens:
- Chain 'A':
Compound: hla class I histocompatibility antigen
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1w72a1, d1w72a2 - Chain 'B':
Compound: Beta-2-microglobulin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1w72b_ - Chain 'C':
Compound: melanoma-associated antigen 1
Database cross-references and differences (RAF-indexed):
- Chain 'D':
Compound: hla class I histocompatibility antigen
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1w72d1, d1w72d2 - Chain 'E':
Compound: Beta-2-microglobulin
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1w72e_ - Chain 'F':
Compound: melanoma-associated antigen 1
Database cross-references and differences (RAF-indexed):
- Chain 'H':
Compound: hyb3 heavy chain
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1w72h1, d1w72h2 - Chain 'I':
Compound: hyb3 heavy chain
Species: HOMO SAPIENS
Database cross-references and differences (RAF-indexed):
Domains in SCOP 1.75: d1w72i1, d1w72i2 - Chain 'L':
Compound: hyb3 light chain
Species: HOMO SAPIENS
Domains in SCOP 1.75: d1w72l1, d1w72l2 - Chain 'M':
Compound: hyb3 light chain
Species: HOMO SAPIENS
Domains in SCOP 1.75: d1w72m1, d1w72m2 - Heterogens: GOL, HOH
PDB Chain Sequences:
- Chain 'A':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72A (A:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqkmeprapwieqegpeyw
dqetrnmkahsqtdranlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdaydg
kdyialnedlrswtaadmaaqitkrkweavhaaeqrrvylegrcvdglrrylengketlq
rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpkpltlrw
- Chain 'B':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72B (B:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'C':
No sequence available.
- Chain 'D':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72D (D:)
gshsmryfftsvsrpgrgeprfiavgyvddtqfvrfdsdaasqkmeprapwieqegpeyw
dqetrnmkahsqtdranlgtlrgyynqsedgshtiqimygcdvgpdgrflrgyrqdaydg
kdyialnedlrswtaadmaaqitkrkweavhaaeqrrvylegrcvdglrrylengketlq
rtdppkthmthhpisdheatlrcwalgfypaeitltwqrdgedqtqdtelvetrpagdgt
fqkwaavvvpsgeeqrytchvqheglpkpltlrw
- Chain 'E':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72E (E:)
miqrtpkiqvysrhpaengksnflncyvsgfhpsdievdllkngeriekvehsdlsfskd
wsfyllyyteftptekdeyacrvnhvtlsqpkivkwdrdm
- Chain 'F':
No sequence available.
- Chain 'H':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72H (H:)
evqlvesggglvqpgrslrlscaasgftfddyamhwvrqapgkglewvsgiswnsgsigy
adsvkgrftisrdnaknslylqmnslraedtavyycargrgfhyyyygmdiwgqgttvtv
ssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
- Chain 'I':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72I (I:)
evqlvesggglvqpgrslrlscaasgftfddyamhwvrqapgkglewvsgiswnsgsigy
adsvkgrftisrdnaknslylqmnslraedtavyycargrgfhyyyygmdiwgqgttvtv
ssastkgpsvfplapsskstsggtaalgclvkdyfpepvtvswnsgaltsgvhtfpavlq
ssglyslssvvtvpssslgtqtyicnvnhkpsntkvdkkvepk
- Chain 'L':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72L (L:)
syvltqppsvsvapgqtaritcggnnigsrsvhwyqqkpgqapvlvvyddsdrpsgiper
fsgsnsgnmatltisrveagdeadyycqvwdsrtdhwvfgggtdltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvap
- Chain 'M':
Sequence; same for both SEQRES and ATOM records: (download)
>1w72M (M:)
syvltqppsvsvapgqtaritcggnnigsrsvhwyqqkpgqapvlvvyddsdrpsgiper
fsgsnsgnmatltisrveagdeadyycqvwdsrtdhwvfgggtdltvlgqpkaapsvtlf
ppsseelqankatlvclisdfypgavtvawkadgspvkagvettkpskqsnnkyaassyl
sltpeqwkshrsyscqvthegstvektvap