PDB entry 1w6k

View 1w6k on RCSB PDB site
Description: Structure of human OSC in complex with Lanosterol
Class: isomerase
Keywords: cyclase, cholesterol, lanosterol, monotopic membrane protein, b-octyl-glucoside, isomerase, steroid biosynthesis
Deposited on 2004-08-19, released 2004-10-29
The last revision prior to the SCOPe 2.08 freeze date was dated 2020-07-29, with a file datestamp of 2020-06-29.
Experiment type: XRAY
Resolution: 2.1 Å
R-factor: N/A
AEROSPACI score: 0.37 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: lanosterol synthase
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w6ka1, d1w6ka2
  • Heterogens: BOG, LAN, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1w6kA (A:)
mtegtclrrrggpyktepatdlgrwrlncergrqtwtylqderagreqtgleayalgldt
knyfkdlpkahtafegalngmtfyvglqaedghwtgdyggplfllpgllitchvariplp
agyreeivrylrsvqlpdggwglhiedkstvfgtalnyvslrilgvgpddpdlvrarnil
hkkggavaipswgkfwlavlnvysweglntlfpemwlfpdwapahpstlwchcrqvylpm
sycyavrlsaaedplvqslrqelyvedfasidwlaqrnnvapdelytphswllrvvyall
nlyehhhsahlrqravqklyehivaddrftksisigpisktinmlvrwyvdgpastafqe
hvsripdylwmgldgmkmqgtngsqiwdtafaiqalleagghhrpefssclqkaheflrl
sqvpdnppdyqkyyrqmrkggfsfstldcgwivsdctaealkavlllqekcphvtehipr
erlcdavavllnmrnpdggfatyetkrgghllellnpsevfgdimidytyvectsavmqa
lkyfhkrfpehraaeiretltqglefcrrqqradgswegswgvcftygtwfgleafacmg
qtyrdgtacaevsracdfllsrqmadggwgedfesceerryvqsaqsqihntcwammglm
avrhpdieaqergvrcllekqlpngdwpqeniagvfnkscaisytsyrnifpiwalgrfs
qlyperalaghp

    Sequence, based on observed residues (ATOM records): (download) 
    >1w6kA (A:)
clrrrggpyktepatdlgrwrlncergrqtwtylqdagreqtgleayalgldtknyfkdl
pkahtafegalngmtfyvglqaedghwtgdyggplfllpgllitchvariplpagyreei
vrylrsvqlpdggwglhiedkstvfgtalnyvslrilgvgpddpdlvrarnilhkkggav
aipswgkfwlavlnvysweglntlfpemwlfpdwapahpstlwchcrqvylpmsycyavr
lsaaedplvqslrqelyvedfasidwlaqrnnvapdelytphswllrvvyallnlyehhh
sahlrqravqklyehivaddrftksisigpisktinmlvrwyvdgpastafqehvsripd
ylwmgldgmkmqgtngsqiwdtafaiqalleagghhrpefssclqkaheflrlsqvpdnp
pdyqkyyrqmrkggfsfstldcgwivsdctaealkavlllqekcphvtehiprerlcdav
avllnmrnpdggfatyetkrgghllellnpsevfgdimidytyvectsavmqalkyfhkr
fpehraaeiretltqglefcrrqqradgswegswgvcftygtwfgleafacmgqtyrdgt
acaevsracdfllsrqmadggwgedfesceerryvqsaqsqihntcwammglmavrhpdi
eaqergvrcllekqlpngdwpqeniagvfnkscaisytsyrnifpiwalgrfsqlypera
laghp