PDB entry 1w5y

View 1w5y on RCSB PDB site
Description: hiv-1 protease in complex with fluoro substituted diol-based c2-symmetric inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: hydrolase/hydrolase inhibitor, hydrolase, dimer, protein-inhibitor complex
Deposited on 2004-08-10, released 2004-10-06
The last revision prior to the SCOPe 2.06 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: 0.188
AEROSPACI score: 0.49 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1w5ya_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.06: d1w5yb_
  • Heterogens: BE6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1w5yA (A:)
adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >1w5yA (A:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1w5yB (B:)
adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >1w5yB (B:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf