PDB entry 1w5y

View 1w5y on RCSB PDB site
Description: HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2004-08-10, released 2004-10-06
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 1.9 Å
R-factor: N/A
AEROSPACI score: 0.35 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w5ya_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w5yb_
  • Heterogens: BE6, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1w5yA (A:)
adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >1w5yA (A:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1w5yB (B:)
adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf

    Sequence, based on observed residues (ATOM records): (download) 
    >1w5yB (B:)
pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
qilieicghkaigtvlvgptpvniigrnlltqigctlnf