PDB entry 1w5w

View 1w5w on RCSB PDB site
Description: HIV-1 protease in complex with fluoro substituted diol-based C2- symmetric inhibitor
Class: hydrolase/hydrolase inhibitor
Keywords: HYDROLASE/HYDROLASE INHIBITOR, HYDROLASE, DIMER, PROTEIN-INHIBITOR COMPLEX, HYDROLASE-HYDROLASE INHIBITOR complex
Deposited on 2004-08-10, released 2004-12-22
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-17, with a file datestamp of 2018-01-12.
Experiment type: XRAY
Resolution: 1.8 Å
R-factor: N/A
AEROSPACI score: 0.38 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Pol polyprotein
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w5wa_
  • Chain 'B':
    Compound: Pol polyprotein
    Species: HUMAN IMMUNODEFICIENCY VIRUS [TaxId:12721]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w5wb_
  • Heterogens: BE4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1w5wA (A:)
    adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
    iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w5wA (A:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1w5wB (B:)
    adrqgtvsfnfpqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmigg
    iggfikvrqydqilieicghkaigtvlvgptpvniigrnlltqigctlnf
    

    Sequence, based on observed residues (ATOM records): (download)
    >1w5wB (B:)
    pqitlwqrplvtikiggqlkealldtgaddtvleemslpgrwkpkmiggiggfikvrqyd
    qilieicghkaigtvlvgptpvniigrnlltqigctlnf