PDB entry 1w2x

View 1w2x on RCSB PDB site
Description: crystal structure of the carboxyltransferase domain of acetyl-coenzyme a carboxylase in complex with cp-640186
Class: transferase
Keywords: transferase, acetyl-coa carboxylase, carboxyltransferase, cp-640186, inhibitor, acc, ct, crystal structure
Deposited on 2004-07-09, released 2004-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.8 Å
R-factor: 0.197
AEROSPACI score: 0.27 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: acetyl-coa carboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2xa1, d1w2xa2
  • Chain 'B':
    Compound: acetyl-coa carboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2xb1, d1w2xb2
  • Chain 'C':
    Compound: acetyl-coa carboxylase
    Species: Saccharomyces cerevisiae [TaxId:4932]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2xc1, d1w2xc2
  • Heterogens: RCP, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1w2xA (A:)
gsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltdd
ffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigs
fgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqy
lyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagat
srayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnl
qlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftp
tndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigve
trtvenlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrg
fsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemy
advnaragvlepqgmvgikfrreklldtmnrlddkyrelrsqlsnkslapevhqqiskql
adrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlneeyl
ikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglklesfa
qdlakkirsdhdnaidglsevikmlstddkekllktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >1w2xA (A:)
piatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffisne
liedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpqed
effnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylyltse
gmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsrayhd
iftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnlqlggtq
imynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptndety
dvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtven
lipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrgfsggqr
dmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvnar
agvlepqgmvgikfrreklldtmnrlellpiygqislqfadlhdrssrmvakgviskele
wtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswypasvdheddrqvatw
ieenyktlddklkglklesfaq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1w2xB (B:)
gsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltdd
ffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigs
fgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqy
lyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagat
srayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnl
qlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftp
tndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigve
trtvenlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrg
fsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemy
advnaragvlepqgmvgikfrreklldtmnrlddkyrelrsqlsnkslapevhqqiskql
adrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlneeyl
ikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglklesfa
qdlakkirsdhdnaidglsevikmlstddkekllktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >1w2xB (B:)
piatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffisne
liedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpqed
effnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylyltse
gmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagatsrayhd
iftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnlqlggtq
imynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptndety
dvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtven
lipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrgfsggqr
dmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvnar
agvlepqgmvgikfrreklldtmnrlellpiygqislqfadlhdrssrmvakgviskele
wtearrfffwrlrrrlneeylikrlshqvgeasrlekiarirswypasvdheddrqvatw
ieenyktlddklkglk

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1w2xC (C:)
gsmhlrpiatpypvkewlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltdd
ffisneliedengelteverepganaigmvafkitvktpeyprgrqfvvvanditfkigs
fgpqedeffnkvteyarkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqy
lyltsegmetlkkfdkensvltertvingeerfviktiigsedglgveclrgsgliagat
srayhdiftitlvtcrsvgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnl
qlggtqimynngvshltavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftp
tndetydvrwmiegretesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigve
trtvenlipadpanpnsaetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrg
fsggqrdmfnevlkygsfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemy
advnaragvlepqgmvgikfrreklldtmnrlddkyrelrsqlsnkslapevhqqiskql
adrerellpiygqislqfadlhdrssrmvakgviskelewtearrfffwrlrrrlneeyl
ikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktlddklkglklesfa
qdlakkirsdhdnaidglsevikmlstddkekllktlk

    Sequence, based on observed residues (ATOM records): (download) 
    >1w2xC (C:)
wlqpkrykahlmgttyvydfpelfrqasssqwknfsadvkltddffisneliedengelt
everepganaigmvafkitvktpeyprgrqfvvvanditfkigsfgpqedeffnkvteya
rkrgipriylaansgarigmaeeivplfqvawndaanpdkgfqylyltsegmetlkkfdk
ensvltertvingeerfviktiigsedglgveclrgsgliagatsrayhdiftitlvtcr
svgigaylvrlgqraiqvegqpiiltgapainkmlgrevytsnlqlggtqimynngvshl
tavddlagvekivewmsyvpakrnmpvpiletkdtwdrpvdftptndetydvrwmiegre
tesgfeyglfdkgsffetlsgwakgvvvgrarlggiplgvigvetrtvenlipadpanpn
saetliqepgqvwhpnsafktaqaindfnngeqlpmmilanwrgfsggqrdmfnevlkyg
sfivdalvdykqpiiiyipptgelrggswvvvdptinadqmemyadvnaragvlepqgmv
gikfrreklldtmnrlellpiygqislqfadlhdrssrmvakgviskelewtearrfffw
rlrrrlneeylikrlshqvgeasrlekiarirswypasvdheddrqvatwieenyktldd
klkglk