PDB entry 1w2c

View 1w2c on RCSB PDB site
Description: Human Inositol (1,4,5) trisphosphate 3-kinase complexed with Mn2+/AMPPNP/Ins(1,4,5)P3
Class: transferase
Keywords: inositol phosphate kinase, amppnp, ip3, transferase
Deposited on 2004-07-01, released 2004-09-09
The last revision prior to the SCOPe 2.08 freeze date was dated 2018-01-24, with a file datestamp of 2018-01-19.
Experiment type: XRAY
Resolution: 1.95 Å
R-factor: N/A
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: inositol-trisphosphate 3-kinase a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2ca_
  • Chain 'B':
    Compound: inositol-trisphosphate 3-kinase a
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1w2cb_
  • Heterogens: ANP, I3P, MN, SO4, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence; same for both SEQRES and ATOM records: (download) 
    >1w2cA (A:)
sfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlqdlldgfd
gpcvldckmgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqravtkprym
qwregisssttlgfriegikkadgscstdfkttrsreqvlrvfeefvqgdeevlrrylnr
lqqirdtlevseffrrhevigssllfvhdhchragvwlidfgkttplpdgqildhrrpwe
egnredgyllgldnligilaslaer

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1w2cB (B:)
sfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlqdlldgfd
gpcvldckmgvrtyleeeltkarerpklrkdmykkmlavdpeapteeehaqravtkprym
qwregisssttlgfriegikkadgscstdfkttrsreqvlrvfeefvqgdeevlrrylnr
lqqirdtlevseffrrhevigssllfvhdhchragvwlidfgkttplpdgqildhrrpwe
egnredgyllgldnligilaslaer

    Sequence, based on observed residues (ATOM records): (download) 
    >1w2cB (B:)
sfkaagtsglilkrcseperyclarlmadalrgcvpafhgvverdgesylqlqdlldgfd
gpcvldckmgvrtyleeeltkklrkdmykkmlavdpavtkprymqwregisssttlgfri
egikkadgscstdfkttrsreqvlrvfeefvqgdeevlrrylnrlqqirdtlevseffrr
hevigssllfvhdhchragvwlidfgkttplpdgqildhrrpweegnredgyllgldnli
gilaslaer