PDB entry 1vyh

View 1vyh on RCSB PDB site
Description: paf-ah holoenzyme: lis1/alfa2
Class: hydrolase
Keywords: lissencephaly, acetylhydrolase, platelet activacting factor, regulator of cytoplasmic dynein, hydrolase, cell division, mitosis, neurogenesis, cytoskeleton
Deposited on 2004-04-30, released 2005-05-26
The last revision prior to the SCOP 1.73 freeze date was dated 2006-05-03, with a file datestamp of 2007-06-04.
Experiment type: XRAY
Resolution: 3.4 Å
R-factor: 0.265
AEROSPACI score: 0.07 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyha1
  • Chain 'B':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhb1
  • Chain 'C':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'D':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'E':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhe1
  • Chain 'F':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhf1
  • Chain 'G':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'H':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'I':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhi1
  • Chain 'J':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhj1
  • Chain 'K':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'L':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'M':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhm1
  • Chain 'N':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhn1
  • Chain 'O':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'P':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'Q':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhq1
  • Chain 'R':
    Compound: platelet-activating factor acetylhydrolase ib beta subunit
    Species: HOMO SAPIENS
    Database cross-references and differences (RAF-indexed): Domains in SCOP 1.73: d1vyhr1
  • Chain 'S':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)
  • Chain 'T':
    Compound: platelet-activating factor acetylhydrolase ib alpha subunit
    Species: MUS MUSCULUS
    Database cross-references and differences (RAF-indexed):
    • Uniprot P63005
      • conflict (198)
      • conflict (275)

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1vyhA (A:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhA (A:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1vyhB (B:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhB (B:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'C':
    No sequence available.

  • Chain 'D':
    No sequence available.

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1vyhE (E:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhE (E:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1vyhF (F:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhF (F:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'G':
    No sequence available.

  • Chain 'H':
    No sequence available.

  • Chain 'I':
    Sequence, based on SEQRES records: (download) 
    >1vyhI (I:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhI (I:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'J':
    Sequence, based on SEQRES records: (download) 
    >1vyhJ (J:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhJ (J:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'K':
    No sequence available.

  • Chain 'L':
    No sequence available.

  • Chain 'M':
    Sequence, based on SEQRES records: (download) 
    >1vyhM (M:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhM (M:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'N':
    Sequence, based on SEQRES records: (download) 
    >1vyhN (N:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhN (N:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'O':
    No sequence available.

  • Chain 'P':
    No sequence available.

  • Chain 'Q':
    Sequence, based on SEQRES records: (download) 
    >1vyhQ (Q:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhQ (Q:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'R':
    Sequence, based on SEQRES records: (download) 
    >1vyhR (R:)
msqgdsnpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwr
elfsplhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggiea
ivqlintrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfv
hsdgaischdmfdflhltgggyakickplhelimqlleetpeekqttia

    Sequence, based on observed residues (ATOM records): (download) 
    >1vyhR (R:)
snpaaiphaaediqgddrwmsqhnrfvldckdkepdvlfvgdsmvqlmqqyeiwrelfsp
lhalnfgiggdttrhvlwrlkngelenikpkvivvwvgtnnhentaeevaggieaivqli
ntrqpqakiivlgllprgekpnplrqknakvnqllkvslpklanvqlldtdggfvhsdga
ischdmfdflhltgggyakickplhelimqlleetpee

  • Chain 'S':
    No sequence available.

  • Chain 'T':
    No sequence available.