PDB entry 1vs8

View 1vs8 on RCSB PDB site
Description: Crystal structure of the bacterial ribosome from escherichia coli in complex with the antibiotic kasugamyin at 3.5a resolution. this file contains the 50s subunit of one 70s ribosome. the entire crystal structure contains two 70s ribosomes and is described in remark 400.
Class: ribosome
Keywords: ribosome, kasugamycin
Deposited on 2006-08-04, released 2006-09-26
The last revision prior to the SCOPe 2.08 freeze date was dated 2014-12-10, with a file datestamp of 2014-12-05.
Experiment type: XRAY
Resolution: 3.46 Å
R-factor: 0.279
AEROSPACI score: 0.02 (click here for full SPACI score report)

Chains and heterogens:

  • Chain '0':
    Compound: 50S ribosomal protein L32
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs801
  • Chain '1':
    Compound: 50S ribosomal protein L33
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs811
  • Chain '2':
    Compound: 50S ribosomal protein L34
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs821
  • Chain '3':
    Compound: 50S ribosomal protein L35
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs831
  • Chain '4':
    Compound: 50S ribosomal protein L36
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs841
  • Chain 'A':
    Compound: 5S ribosomal RNA
    Species: Escherichia coli [TaxId:562]
  • Chain 'B':
    Compound: 23S ribosomal RNA
    Species: Escherichia coli [TaxId:562]
  • Chain 'C':
    Compound: 50S ribosomal protein L2
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8c1, d1vs8c2
  • Chain 'D':
    Compound: 50S ribosomal protein L3
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8d1
  • Chain 'E':
    Compound: 50S ribosomal protein L4
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8e1
  • Chain 'F':
    Compound: 50S ribosomal protein L5
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8f1
  • Chain 'G':
    Compound: 50S ribosomal protein L6
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8g1, d1vs8g2
  • Chain 'H':
    Compound: 50S ribosomal protein L9
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8h1, d1vs8h2
  • Chain 'I':
    Compound: 50S ribosomal protein L11
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8i1, d1vs8i2
  • Chain 'J':
    Compound: 50S ribosomal protein L13
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8j1
  • Chain 'K':
    Compound: 50S ribosomal protein L14
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8k1
  • Chain 'L':
    Compound: 50S ribosomal protein L15
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8l1
  • Chain 'M':
    Compound: 50S ribosomal protein L16
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8m1
  • Chain 'N':
    Compound: 50S ribosomal protein L17
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8n1
  • Chain 'O':
    Compound: 50S ribosomal protein L18
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8o1
  • Chain 'P':
    Compound: 50S ribosomal protein L19
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8p1
  • Chain 'Q':
    Compound: 50S ribosomal protein L20
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8q1
  • Chain 'R':
    Compound: 50S ribosomal protein L21
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8r1
  • Chain 'S':
    Compound: 50S ribosomal protein L22
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8s1
  • Chain 'T':
    Compound: 50S ribosomal protein L23
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8t1
  • Chain 'U':
    Compound: 50S ribosomal protein L24
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8u1
  • Chain 'V':
    Compound: 50S ribosomal protein L25
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8v1
  • Chain 'W':
    Compound: 50S ribosomal protein L27
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8w1
  • Chain 'X':
    Compound: 50S ribosomal protein L29
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8x1
  • Chain 'Y':
    Compound: 50S ribosomal protein L30
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8y1
  • Chain 'Z':
    Compound: 50S ribosomal protein L31
    Species: Escherichia coli [TaxId:562]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.08: d1vs8z1
  • Heterogens: MG, HOH

PDB Chain Sequences:

  • Chain '0':
    Sequence, based on SEQRES records: (download)
    >1vs80 (0:)
    mavqqnkptrskrgmrrshdaltavtslsvdktsgekhlrhhitadgyyrgrkviak
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs80 (0:)
    avqqnkptrskrgmrrshdaltavtslsvdktsgekhlrhhitadgyyrgrkviak
    

  • Chain '1':
    Sequence, based on SEQRES records: (download)
    >1vs81 (1:)
    makgirekiklvssagtghfytttknkrtkpeklelkkfdpvvrqhviykeakik
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs81 (1:)
    akgirekiklvssagtghfytttknkrtkpeklelkkfdpvvrqhviykeakik
    

  • Chain '2':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs82 (2:)
    mkrtfqpsvlkrnrshgfrarmatkngrqvlarrrakgrarltvsk
    

  • Chain '3':
    Sequence, based on SEQRES records: (download)
    >1vs83 (3:)
    mpkiktvrgaakrfkktgkggfkhkhanlrhiltkkatkrkrhlrpkamvskgdlglvia
    clpya
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs83 (3:)
    pkiktvrgaakrfkktgkggfkhkhanlrhiltkkatkrkrhlrpkamvskgdlglviac
    lpya
    

  • Chain '4':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs84 (4:)
    mkvrasvkklcrnckivkrdgvirvicsaepkhkqrqg
    

  • Chain 'A':
    No sequence available.

  • Chain 'B':
    No sequence available.

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1vs8C (C:)
    mavvkckptspgrrhvvkvvnpelhkgkpfaplleknsksggrnnngrittrhiggghkq
    ayrivdfkrnkdgipavverleydpnrsanialvlykdgerryilapkglkagdqiqsgv
    daaikpgntlpmrnipvgstvhnvemkpgkggqlarsagtyvqivardgayvtlrlrsge
    mrkveadcratlgevgnaehmlrvlgkagaarwrgvrptvrgtamnpvdhphgggegrnf
    gkhpvtpwgvqtkgkktrsnkrtdkfivrrrsk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8C (C:)
    vkckptspgrrhvvkvvnpelhkgkpfaplleknsksggrnnngrittrhiggghkqayr
    ivdfkrnkdgipavverleydpnrsanialvlykdgerryilapkglkagdqiqsgvdaa
    ikpgntlpmrnipvgstvhnvemkpgkggqlarsagtyvqivardgayvtlrlrsgemrk
    veadcratlgevgnaehmlrvlgkagaarwrgvrptvrgtamnpvdhphgggegrnfgkh
    pvtpwgvqtkgkktrsnkrtdkfivrr
    

  • Chain 'D':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8D (D:)
    miglvgkkvgmtriftedgvsipvtvieveanrvtqvkdlandgyraiqvttgakkanrv
    tkpeaghfakagveagrglwefrlaegeeftvgqsisvelfadvkkvdvtgtskgkgfag
    tvkrwnfrtqdathgnslshrvpgsigqnqtpgkvfkgkkmagqmgnervtvqsldvvrv
    daernlllvkgavpgatgsdlivkpavka
    

  • Chain 'E':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8E (E:)
    melvlkdaqsaltvsettfgrdfnealvhqvvvayaagarqgtraqktraevtgsgkkpw
    rqkgtgrarsgsikspiwrsggvtfaarpqdhsqkvnkkmyrgalksilselvrqdrliv
    vekfsveapktkllaqklkdmaledvliitgeldenlflaarnlhkvdvrdatgidpvsl
    iafdkvvmtadavkqveemla
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1vs8F (F:)
    maklhdyykdevvkklmtefnynsvmqvprvekitlnmgvgeaiadkklldnaaadlaai
    sgqkplitkarksvagfkirqgypigckvtlrgermwefferlitiavprirdfrglsak
    sfdgrgnysmgvreqiifpeidydkvdrvrgldititttaksdeegrallaafdfpfrk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8F (F:)
    aklhdyykdevvkklmtefnynsvmqvprvekitlnmgvgeaiadkklldnaaadlaais
    gqkplitkarksvagfkirqgypigckvtlrgermwefferlitiavprirdfrglsaks
    fdgrgnysmgvreqiifpeidydkvdrvrgldititttaksdeegrallaafdfpfrk
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1vs8G (G:)
    msrvakapvvvpagvdvkingqvitikgkngeltrtlndavevkhadntltfgprdgyad
    gwaqagtarallnsmvigvtegftkklqlvgvgyraavkgnvinlslgfshpvdhqlpag
    itaecptqteivlkgadkqvigqvaadlrayrrpepykgkgvryadevvrtkeakkk
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8G (G:)
    srvakapvvvpagvdvkingqvitikgkngeltrtlndavevkhadntltfgprdgyadg
    waqagtarallnsmvigvtegftkklqlvgvgyraavkgnvinlslgfshpvdhqlpagi
    taecptqteivlkgadkqvigqvaadlrayrrpepykgkgvryadevvrtkeakkk
    

  • Chain 'H':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8H (H:)
    mqvilldkvanlgslgdqvnvkagyarnflvpqgkavpatkknieffearraeleaklae
    vlaaanaraekinaletvtiaskagdegklfgsigtrdiadavtaagvevaksevrlpng
    vlrttgehevsfqvhsevfakvivnvvae
    

  • Chain 'I':
    Sequence, based on SEQRES records: (download)
    >1vs8I (I:)
    makkvqayvklqvaagmanpsppvgpalgqqgvnimefckafnaktdsiekglpipvvit
    vyadrsftfvtktppaavllkkaagiksgsgkpnkdkvgkisraqlqeiaqtkaadmtga
    dieamtrsiegtarsmglvved
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8I (I:)
    akkvqayvklqvaagmanpsppvgpalgqqgvnimefckafnaktdsiekglpipvvitv
    yadrsftfvtktppaavllkkaagiksgsgkpnkdkvgkisraqlqeiaqtkaadmtgad
    ieamtrsiegtarsmglvved
    

  • Chain 'J':
    Sequence, based on SEQRES records: (download)
    >1vs8J (J:)
    mktftakpetvkrdwyvvdatgktlgrlatelarrlrgkhkaeytphvdtgdyiivlnad
    kvavtgnkrtdkvyyhhtghiggikqatfeemiarrpervieiavkgmlpkgplgramfr
    klkvyagnehnhaaqqpqvldi
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8J (J:)
    mktftakpetvkrdwyvvdatgktlgrlatelarrlrgkhkaeytphvdtgdyiivlnad
    kvavtgnkrtdkvyyhhtghiggikqatfeemiarrpervieiavkgmlpkgplgramfr
    klkvyagnehnhaaqqpqvl
    

  • Chain 'K':
    Sequence, based on SEQRES records: (download)
    >1vs8K (K:)
    miqeqtmlnvadnsgarrvmcikvlggshrryagvgdiikitikeaiprgkvkkgdvlka
    vvvrtkkgvrrpdgsvirfdgnacvllnnnseqpigtrifgpvtrelrsekfmkiislap
    evl
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8K (K:)
    iqeqtmlnvadnsgarrvmcikvlggshrryagvgdiikitikeaiprgkvkkgdvlkav
    vvrtkkgvrrpdgsvirfdgnacvllnnnseqpigtrifgpvtrelrsekfmkiislape
    v
    

  • Chain 'L':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8L (L:)
    mrlntlspaegskkagkrlgrgigsglgktggrghkgqksrsgggvrrgfeggqmplyrr
    lpkfgftsrkaaitaeirlsdlakveggvvdlntlkaaniigiqiefakvilagevttpv
    tvrglrvtkgaraaieaaggkiee
    

  • Chain 'M':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8M (M:)
    mlqpkrtkfrkmhkgrnrglaqgtdvsfgsfglkavgrgrltarqieaarramtravkrq
    gkiwirvfpdkpitekplavrmgkgkgnveywvaliqpgkvlyemdgvpeelareafkla
    aaklpikttfvtktvm
    

  • Chain 'N':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8N (N:)
    mrhrksgrqlnrnsshrqamfrnmagslvrheiikttlpkakelrrvveplitlaktdsv
    anrrlafartrdneivaklfnelgprfasraggytrilkcgfragdnapmayielvdrse
    kaeaaae
    

  • Chain 'O':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8O (O:)
    mdkksarirratrarrklqelgatrlvvhrtprhiyaqviapngsevlvaastvekaiae
    qlkytgnkdaaaavgkavaeralekgikdvsfdrsgfqyhgrvqaladaareaglqf
    

  • Chain 'P':
    Sequence, based on SEQRES records: (download)
    >1vs8P (P:)
    msniikqleqeqmkqdvpsfrpgdtvevkvwvvegskkrlqafegvviairnrglhsaft
    vrkisngegvervfqthspvvdsisvkrrgavrkaklyylrertgkaarikerln
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8P (P:)
    sniikqleqeqmkqdvpsfrpgdtvevkvwvvegskkrlqafegvviairnrglhsaftv
    rkisngegvervfqthspvvdsisvkrrgavrkaklyylrertgkaarikerln
    

  • Chain 'Q':
    Sequence, based on SEQRES records: (download)
    >1vs8Q (Q:)
    marvkrgviararhkkilkqakgyygarsrvyrvafqavikagqyayrdrrqrkrqfrql
    wiarinaaarqngisyskfinglkkasveidrkiladiavfdkvaftalvekakaala
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8Q (Q:)
    arvkrgviararhkkilkqakgyygarsrvyrvafqavikagqyayrdrrqrkrqfrqlw
    iarinaaarqngisyskfinglkkasveidrkiladiavfdkvaftalvekakaala
    

  • Chain 'R':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8R (R:)
    myavfqsggkqhrvsegqtvrlekldiatgetvefaevlmiangeevkigvpfvdggvik
    aevvahgrgekvkivkfrrrkhyrkqqghrqwftdvkitgisa
    

  • Chain 'S':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8S (S:)
    metiakhrharssaqkvrlvadlirgkkvsqaldiltytnkkaavlvkkvlesaianaeh
    ndgadiddlkvtkifvdegpsmkrimprakgradrilkrtshitvvvsdr
    

  • Chain 'T':
    Sequence, based on SEQRES records: (download)
    >1vs8T (T:)
    mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevvnt
    lvvkgkvkrhgqrigrrsdwkkayvtlkegqnldfvggae
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8T (T:)
    mireerllkvlraphvsekastameksntivlkvakdatkaeikaavqklfevevevvnt
    lvvkgkvkrhgqrigrrsdwkkayvtlkegqnldfvgga
    

  • Chain 'U':
    Sequence, based on SEQRES records: (download)
    >1vs8U (U:)
    maakirrddevivltgkdkgkrgkvknvlssgkviveginlvkkhqkpvpalnqpggive
    keaaiqvsnvaifnaatgkadrvgfrfedgkkvrffksnsetik
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8U (U:)
    aakirrddevivltgkdkgkrgkvknvlssgkviveginlvkkhqkpvpalnqpggivek
    eaaiqvsnvaifnaatgkadrvgfrfedgkkvrffksnseti
    

  • Chain 'V':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8V (V:)
    mftinaevrkeqgkgasrrlraankfpaiiyggkeaplaieldhdkvmnmqakaefysev
    ltivvdgkeikvkaqdvqrhpykpklqhidfvra
    

  • Chain 'W':
    Sequence, based on SEQRES records: (download)
    >1vs8W (W:)
    mahkkaggstrngrdseakrlgvkrfggesvlagsiivrqrgtkfhaganvgcgrdhtlf
    akadgkvkfevkgpknrkfisieae
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8W (W:)
    ahkkaggstrngrdseakrlgvkrfggesvlagsiivrqrgtkfhaganvgcgrdhtlfa
    kadgkvkfevkgpknrkfisieae
    

  • Chain 'X':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8X (X:)
    mkakelreksveelntellnllreqfnlrmqaasgqlqqshllkqvrrdvarvktllnek
    aga
    

  • Chain 'Y':
    Sequence, based on SEQRES records: (download)
    >1vs8Y (Y:)
    maktikitqtrsaigrlpkhkatllglglrrightveredtpairgminavsfmvkvee
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vs8Y (Y:)
    aktikitqtrsaigrlpkhkatllglglrrightveredtpairgminavsfmvkvee
    

  • Chain 'Z':
    Sequence; same for both SEQRES and ATOM records: (download)
    >1vs8Z (Z:)
    mkkdihpkyeeitascscgnvmkirstvghdlnldvcskchpfftgkqrdvatggrvdrf
    nkrfnipgsk