PDB entry 1vha

View 1vha on RCSB PDB site
Description: Crystal structure of 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
Class: Lyase
Keywords: structural genomics, Lyase
Deposited on 2003-12-01, released 2003-12-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2011-07-13, with a file datestamp of 2011-05-08.
Experiment type: XRAY
Resolution: 2.35 Å
R-factor: 0.244
AEROSPACI score: 0.32 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Haemophilus influenzae [TaxId:727]
    Gene: ISPF, HI0671
    Database cross-references and differences (RAF-indexed):
    • Uniprot P44815 (3-159)
      • cloning artifact (1-2)
      • modified residue (107)
      • modified residue (114)
    Domains in SCOPe 2.07: d1vhaa1, d1vhaa2
  • Chain 'B':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Haemophilus influenzae [TaxId:727]
    Gene: ISPF, HI0671
    Database cross-references and differences (RAF-indexed):
    • Uniprot P44815 (3-159)
      • cloning artifact (1-2)
      • modified residue (107)
      • modified residue (114)
    Domains in SCOPe 2.07: d1vhab1, d1vhab2
  • Chain 'C':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Haemophilus influenzae [TaxId:727]
    Gene: ISPF, HI0671
    Database cross-references and differences (RAF-indexed):
    • Uniprot P44815 (3-159)
      • cloning artifact (1-2)
      • modified residue (107)
      • modified residue (114)
    Domains in SCOPe 2.07: d1vhac1, d1vhac2
  • Chain 'D':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Haemophilus influenzae [TaxId:727]
    Gene: ISPF, HI0671
    Database cross-references and differences (RAF-indexed):
    • Uniprot P44815 (3-159)
      • cloning artifact (1-2)
      • modified residue (107)
      • modified residue (114)
    Domains in SCOPe 2.07: d1vhad1, d1vhad2
  • Chain 'E':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Haemophilus influenzae [TaxId:727]
    Gene: ISPF, HI0671
    Database cross-references and differences (RAF-indexed):
    • Uniprot P44815 (3-159)
      • cloning artifact (1-2)
      • modified residue (107)
      • modified residue (114)
    Domains in SCOPe 2.07: d1vhae1, d1vhae2
  • Chain 'F':
    Compound: 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase
    Species: Haemophilus influenzae [TaxId:727]
    Gene: ISPF, HI0671
    Database cross-references and differences (RAF-indexed):
    • Uniprot P44815 (3-159)
      • cloning artifact (1-2)
      • modified residue (107)
      • modified residue (114)
    Domains in SCOPe 2.07: d1vhaf1, d1vhaf2
  • Heterogens: MN, POP, ACY, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download) 
    >1vhaA (A:)
mslirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdi
gklfpdtdmqyknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakia
edlqcdieqvnvkattteklgftgrqegiaceavallirqeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1vhaA (A:)
slirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdig
klfpknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakiaedlqcdi
eqvnvkattteklgftgrqegiaceavallirq

  • Chain 'B':
    Sequence, based on SEQRES records: (download) 
    >1vhaB (B:)
mslirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdi
gklfpdtdmqyknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakia
edlqcdieqvnvkattteklgftgrqegiaceavallirqeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1vhaB (B:)
slirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdig
klfpnadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakiaedlqcdie
qvnvkattteklgftgrqegiaceavallirq

  • Chain 'C':
    Sequence, based on SEQRES records: (download) 
    >1vhaC (C:)
mslirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdi
gklfpdtdmqyknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakia
edlqcdieqvnvkattteklgftgrqegiaceavallirqeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1vhaC (C:)
slirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdig
klfpknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakiaedlqcdi
eqvnvkattteklgftgrqegiaceavallirq

  • Chain 'D':
    Sequence, based on SEQRES records: (download) 
    >1vhaD (D:)
mslirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdi
gklfpdtdmqyknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakia
edlqcdieqvnvkattteklgftgrqegiaceavallirqeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1vhaD (D:)
slirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdig
klfpnadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakiaedlqcdie
qvnvkattteklgftgrqegiaceavallirq

  • Chain 'E':
    Sequence, based on SEQRES records: (download) 
    >1vhaE (E:)
mslirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdi
gklfpdtdmqyknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakia
edlqcdieqvnvkattteklgftgrqegiaceavallirqeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1vhaE (E:)
slirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdig
klfpnadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakiaedlqcdie
qvnvkattteklgftgrqegiaceavallirq

  • Chain 'F':
    Sequence, based on SEQRES records: (download) 
    >1vhaF (F:)
mslirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdi
gklfpdtdmqyknadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakia
edlqcdieqvnvkattteklgftgrqegiaceavallirqeggshhhhhh

    Sequence, based on observed residues (ATOM records): (download) 
    >1vhaF (F:)
slirighgfdvhafgedrpliiggvevpyhtgfiahsdgdvalhaltdailgaaalgdig
klfpnadsrgllreafrqvqekgykignvditiiaqapkmrphidamrakiaedlqcdie
qvnvkattteklgftgrqegiaceavallirq