PDB entry 1vg9

View 1vg9 on RCSB PDB site
Description: The crystal structures of the REP-1 protein in complex with C-terminally truncated Rab7 protein
Class: protein binding/protein transport
Keywords: rab prenylation, post-translational modification, protein binding-protein transport complex
Deposited on 2004-04-23, released 2004-07-20
The last revision prior to the SCOPe 2.07 freeze date was dated 2017-10-04, with a file datestamp of 2017-09-29.
Experiment type: XRAY
Resolution: 2.5 Å
R-factor: N/A
AEROSPACI score: 0.21 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: Rab proteins geranylgeranyltransferase component A 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37727
      • engineered (230)
      • engineered (461)
      • engineered (472)
      • engineered (482)
    Domains in SCOPe 2.07: d1vg9a1, d1vg9a2
  • Chain 'B':
    Compound: Ras-related protein Rab-7
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1vg9b_
  • Chain 'C':
    Compound: Rab proteins geranylgeranyltransferase component A 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37727
      • engineered (230)
      • engineered (461)
      • engineered (472)
      • engineered (482)
    Domains in SCOPe 2.07: d1vg9c1, d1vg9c2
  • Chain 'D':
    Compound: Ras-related protein Rab-7
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1vg9d_
  • Chain 'E':
    Compound: Rab proteins geranylgeranyltransferase component A 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37727
      • engineered (230)
      • engineered (461)
      • engineered (472)
      • engineered (482)
    Domains in SCOPe 2.07: d1vg9e1, d1vg9e2
  • Chain 'F':
    Compound: Ras-related protein Rab-7
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1vg9f_
  • Chain 'G':
    Compound: Rab proteins geranylgeranyltransferase component A 1
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed):
    • Uniprot P37727
      • engineered (230)
      • engineered (461)
      • engineered (472)
      • engineered (482)
    Domains in SCOPe 2.07: d1vg9g1, d1vg9g2
  • Chain 'H':
    Compound: Ras-related protein Rab-7
    Species: Rattus norvegicus [TaxId:10116]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1vg9h_
  • Heterogens: MG, K, GDP, P33, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1vg9A (A:)
    madnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlk
    eyqenndvvtensmwqeqileneeaiplsskdktiqhvevfcyasqdlhkdveeagalqk
    nhasvtsaqsaeaaeaaetsclptaveplsmgsceipaeqsqcpgpesspevndaeatgk
    kensdakssteepsenvpkvqdntetpkknritysqiikegrrfnidlvskllysrglli
    dlliksnvsryaefknitrilafregtveqvpcsradvfnskqltmvekrmlmkfltfcv
    eyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsettsctvdglkatkkflq
    clgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclvvdkesrkckavidqf
    gqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtdadqqvsiltvpaeepg
    sfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklftpyteieaeneqvek
    prllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfqqicpned
    fcpappnpedivldgdssqqevpessvtpetnsetpkestvlgnpeepse
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9A (A:)
    adnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlke
    yqmwqeqileneeaiplsskdktiqhvevfcyasqdnritysqiikegrrfnidlvskll
    ysrgllidlliksnvsryaefknitrilafregtveqvpcsradvfnskqltmvekrmlm
    kfltfcveyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsettsctvdglk
    atkkflqclgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclvvdkesrkc
    kavidqfgqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtdadqqvsilt
    vpaeepgsfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklftpyteiea
    eneqvekprllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfq
    qicpnedfcpappnpedivld
    

  • Chain 'B':
    Sequence, based on SEQRES records: (download)
    >1vg9B (B:)
    mtsrkkvllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddrlvtmq
    iwdtagqerfqslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpf
    vvlgnkidlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqetev
    elyne
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9B (B:)
    kvllkviilgdsgvgktslmnqyvnkkfsnigadfltkevmvddrlvtmqiwdtagqerf
    qslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpfvvlgnkidle
    nrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqete
    

  • Chain 'C':
    Sequence, based on SEQRES records: (download)
    >1vg9C (C:)
    madnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlk
    eyqenndvvtensmwqeqileneeaiplsskdktiqhvevfcyasqdlhkdveeagalqk
    nhasvtsaqsaeaaeaaetsclptaveplsmgsceipaeqsqcpgpesspevndaeatgk
    kensdakssteepsenvpkvqdntetpkknritysqiikegrrfnidlvskllysrglli
    dlliksnvsryaefknitrilafregtveqvpcsradvfnskqltmvekrmlmkfltfcv
    eyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsettsctvdglkatkkflq
    clgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclvvdkesrkckavidqf
    gqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtdadqqvsiltvpaeepg
    sfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklftpyteieaeneqvek
    prllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfqqicpned
    fcpappnpedivldgdssqqevpessvtpetnsetpkestvlgnpeepse
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9C (C:)
    dnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlkey
    qenndvvtensmwqeqileneeaiplsskdktiqhvevfcyasqdritysqiikegrrfn
    idlvskllysrgllidlliksnvsryaefknitrilafregtveqvpcsradvfnskqlt
    mvekrmlmkfltfcveyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsett
    sctvdglkatkkflqclgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclv
    vdkesrkckavidqfgqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtda
    dqqvsiltvpaeepgsfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklf
    tpyteekprllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfq
    qicpnedfcpappnpedivldg
    

  • Chain 'D':
    Sequence, based on SEQRES records: (download)
    >1vg9D (D:)
    mtsrkkvllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddrlvtmq
    iwdtagqerfqslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpf
    vvlgnkidlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqetev
    elyne
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9D (D:)
    kvllkviilgdsgvgktslmnqyvnkkfsnqyigadfltkevmvddrlvtmqiwdtagqe
    rfqslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpfvvlgnkid
    lenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqeteve
    

  • Chain 'E':
    Sequence, based on SEQRES records: (download)
    >1vg9E (E:)
    madnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlk
    eyqenndvvtensmwqeqileneeaiplsskdktiqhvevfcyasqdlhkdveeagalqk
    nhasvtsaqsaeaaeaaetsclptaveplsmgsceipaeqsqcpgpesspevndaeatgk
    kensdakssteepsenvpkvqdntetpkknritysqiikegrrfnidlvskllysrglli
    dlliksnvsryaefknitrilafregtveqvpcsradvfnskqltmvekrmlmkfltfcv
    eyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsettsctvdglkatkkflq
    clgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclvvdkesrkckavidqf
    gqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtdadqqvsiltvpaeepg
    sfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklftpyteieaeneqvek
    prllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfqqicpned
    fcpappnpedivldgdssqqevpessvtpetnsetpkestvlgnpeepse
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9E (E:)
    dnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlkey
    qmwqeqileneeaiplsskdktiqhvevfcyasqdnritysqiikegrrfnidlvsklly
    srgllidlliksnvsryaefknitrilafregtveqvpcsradvfnskqltmvekrmlmk
    fltfcveyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsettsctvdglka
    tkkflqclgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclvvdkesrkck
    avidqfgqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtdadqqvsiltv
    paeepgsfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklftpyteieae
    neqvekprllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfqq
    icpnedfcpappnpedivld
    

  • Chain 'F':
    Sequence, based on SEQRES records: (download)
    >1vg9F (F:)
    mtsrkkvllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddrlvtmq
    iwdtagqerfqslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpf
    vvlgnkidlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqetev
    elyne
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9F (F:)
    kvllkviilgdsgvgktslmnqyvnkkfsnigadfltkevmvddrlvtmqiwdtagqerf
    qslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpfvvlgnkidle
    nrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqet
    

  • Chain 'G':
    Sequence, based on SEQRES records: (download)
    >1vg9G (G:)
    madnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlk
    eyqenndvvtensmwqeqileneeaiplsskdktiqhvevfcyasqdlhkdveeagalqk
    nhasvtsaqsaeaaeaaetsclptaveplsmgsceipaeqsqcpgpesspevndaeatgk
    kensdakssteepsenvpkvqdntetpkknritysqiikegrrfnidlvskllysrglli
    dlliksnvsryaefknitrilafregtveqvpcsradvfnskqltmvekrmlmkfltfcv
    eyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsettsctvdglkatkkflq
    clgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclvvdkesrkckavidqf
    gqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtdadqqvsiltvpaeepg
    sfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklftpyteieaeneqvek
    prllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfqqicpned
    fcpappnpedivldgdssqqevpessvtpetnsetpkestvlgnpeepse
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9G (G:)
    dnlpsdfdvivigtglpesiiaaacsrsgqrvlhvdsrsyyggnwasfsfsgllswlkey
    qenndvvtensmwqeqileneeaiplsskdktiqhvevfcyasqdritysqiikegrrfn
    idlvskllysrgllidlliksnvsryaefknitrilafregtveqvpcsradvfnskqlt
    mvekrmlmkfltfcveyeehpdeyrayegttfseylktqkltpnlqyfvlhsiamtsett
    sctvdglkatkkflqclgrygntpflfplygqgelpqcfcrmcavfggiyclrhsvqclv
    vdkesrkckavidqfgqriiskhfiiedsylsentcsrvqyrqisravlitdgsvlrtda
    dqqvsiltvpaeepgsfavrvielcsstmtcmkgtylvhltcmssktaredlervvqklf
    tpyteekprllwalyfnmrdssdisrdcyndlpsnvyvcsgpdsglgndnavkqaetlfq
    qicpnedfcpappnpedivldg
    

  • Chain 'H':
    Sequence, based on SEQRES records: (download)
    >1vg9H (H:)
    mtsrkkvllkviilgdsgvgktslmnqyvnkkfsnqykatigadfltkevmvddrlvtmq
    iwdtagqerfqslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpf
    vvlgnkidlenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqetev
    elyne
    

    Sequence, based on observed residues (ATOM records): (download)
    >1vg9H (H:)
    kvllkviilgdsgvgktslmnqyvnkkfsnqyigadfltkevmvddrlvtmqiwdtagqe
    rfqslgvafyrgadccvlvfdvtapntfktldswrdefliqasprdpenfpfvvlgnkid
    lenrqvatkraqawcysknnipyfetsakeainveqafqtiarnalkqeteve