PDB entry 1v4s

View 1v4s on RCSB PDB site
Description: Crystal structure of human glucokinase
Class: transferase
Keywords: hexokinase IV, allosteric enzyme, diabetes, TRANSFERASE
Deposited on 2003-11-19, released 2004-03-30
The last revision prior to the SCOPe 2.07 freeze date was dated 2009-02-24, with a file datestamp of 2009-03-01.
Experiment type: XRAY
Resolution: 2.3 Å
R-factor: 0.235
AEROSPACI score: 0.33 (click here for full SPACI score report)

Chains and heterogens:

  • Chain 'A':
    Compound: glucokinase isoform 2
    Species: Homo sapiens [TaxId:9606]
    Database cross-references and differences (RAF-indexed): Domains in SCOPe 2.07: d1v4sa1, d1v4sa2, d1v4sa3
  • Heterogens: GLC, NA, MRK, HOH

PDB Chain Sequences:

  • Chain 'A':
    Sequence, based on SEQRES records: (download)
    >1v4sA (A:)
    maltlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegse
    vgdflsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyiseci
    sdfldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaik
    rrgdfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegr
    mcvntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlv
    denllfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrra
    cesvstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrl
    tpsceitfieseegsgrgaalvsavackkacmlgq
    

    Sequence, based on observed residues (ATOM records): (download)
    >1v4sA (A:)
    tlveqilaefqlqeedlkkvmrrmqkemdrglrletheeasvkmlptyvrstpegsevgd
    flsldlggtnfrvmlvkvgegeegqwsvktkhqmysipedamtgtaemlfdyisecisdf
    ldkhqmkhkklplgftfsfpvrhedidkgillnwtkgfkasgaegnnvvgllrdaikrrg
    dfemdvvamvndtvatmiscyyedhqcevgmivgtgcnacymeemqnvelvegdegrmcv
    ntewgafgdsgeldeflleydrlvdessanpgqqlyekliggkymgelvrlvllrlvden
    llfhgeaseqlrtrgafetrfvsqvesdtgdrkqiynilstlglrpsttdcdivrraces
    vstraahmcsaglagvinrmresrsedvmritvgvdgsvyklhpsfkerfhasvrrltps
    ceitfieseegsgrgaalvsavackkac